73586-40-0Relevant academic research and scientific papers
Synthesis and monoamine oxidase inhibitory activities of α-allenic amines in vivo and in vitro. Different activities of two enantiomeric allenes
Sahlberg,Ross,Fagervall,Ask,Claesson
, p. 1036 - 1042 (2007/10/02)
A series of 15 α-allenic amines, including primary, secondary, and tertiary ones, was synthesized, partly by organocopper chemistry. Their ability to inhibit mouse and rat brain mitochondrial monoamine oxidase (MAO) in vivo and in vitro, respectively, was
Allenes and Acetylenes. XXIV. Synthesis of α-Allenic Amines by Organocuprate Reactions of Acetylenic Aminoethers
Sahlberg, Christer,Claesson, Alf
, p. 179 - 186 (2007/10/02)
Tertiary α-allenic amines 1a - d are formed in good yields in reactions of acetylenic aminoethers with an organocuprate reagent, derived from butylmagnesium bromide and 5-20percent of CuI, in tetrahydrofuran (THF) or THF-diethyl ether 3:1.The overall redu
