73591-17-0

Upstream product

• 67-56-1 methanol 
• 935-02-4 3-Phenyl-2-propynonitrile 
• 48116-06-9 (Z)-2-Cyano-1-phenyl-ethenol anion 
• 74-88-4 methyl iodide 
• 420-04-2 CYANAMID 
• 5873-90-5 methyl benzimidate hydrochloride 
• 80-48-8 methyl p-toluene sulfonate 

Downstream Products

• 67-56-1 methanol 
• 614-16-4 Benzoylacetonitrile 
• 932044-20-7 C₁₇H₂₂N₄O₂ 
• 158495-65-9 4-amino-6-phenyl-1-methyl-2-pyrimidinethione 

Relevant academic research and scientific papers

Piperazine amidines as antiviral agents

This disclosure provides compounds of Formula I as described herein having drug and bio-affecting properties, their pharmaceutical compositions and method of use. In particular, the disclosure is concerned with indole and azaindole piperazine diamide derivatives that possess unique antiviral activity. More particularly, the present disclosure relates to compounds useful for the treatment of HIV and AIDS.

MESOMERIC ANIONS. X. METHYLATION OF ALKALI-METAL DERIVATIVES OF SOME 1,3-KETONITRILES

The effect of polar factors on the relative nucleophilicity of the oxygen and carbon reaction centers in the alkali-metal derivatives of 2-(X-benzoyl)acetonitriles, 2-(X-benzoyl)propionitriles, and 2-(X-phenyl)acetylacetonitriles was investigated.During methylation with methyl iodide and methyl p-toluenesulfonate in DMFA the ratio of the C- and O-methylation products for all the investigated compounds decreases with increase in the accepting power of the substituent X.It was shown that the sensitivity of the C-reaction center to the effect of the substituent X is greater than that of the O-center.