736-50-5

Upstream product

• 40207-03-2 p-Anisidinothioformyl-hydrazin 
• 100-52-7 benzaldehyde 
• 5281-18-5 benzaldehyde, hydrazone 
• 2284-20-0 4-Methoxyphenyl isothiocyanate 

Downstream Products

• 798-29-8 benzaldehyde [3-(4-methoxy-phenyl)-4-oxo-thiazolidin-2-ylidene]-hydrazone 
• 800-40-8 benzaldehyde [3-(4-methoxy-phenyl)-5-methyl-4-oxo-thiazolidin-2-ylidene]-hydrazone 
• 807-51-2 benzaldehyde [3-(4-methoxy-phenyl)-4-oxo-5-phenyl-thiazolidin-2-ylidene]-hydrazone 

Relevant academic research and scientific papers

Synthesis and antibacterial activity of pyridyl thioureas and arylthiosemicarbazones

[N-(2-pyridyl)-N'-(4-(un) substituted] thioureas and (substitutedaryl)thiosemicarbazones were synthesised and evaluated for their antibacterial activity. All aryl thiosemicarbazones showed good activity against Aeromonas hydrophilia and Salmonella typhimuriurn. But none of the pyridyl thioureas showed any prominent activity against tested bacteria.

On the synthesis of fused thiazolo[5,4-d]isoxazoles and a novel rearrangement involving conversion of 5(4H)-isoxazolones to 4(5H)-isoxazolones

The interaction of 4-bromo-3-substituted-(4H)-isoxazol-5-ones (1) with alkyl/aryl thiocarbamides (2), 4-alkyl/aryl thiosemicarbazides (7) and 2, 4-disubstituted thiosemicarbazides (12) afford 5-alkyl/ arylamino-3-substituted-thiazolo [5, 4-d]isoxazoles (3) and 6-amino/anilino-5-alkyl/arylimino-3-substituted-thiazolo[5, 4-d]isoxazoles respectively. An alternate unambiguous one step synthesis is described. The compounds have been characterised by chemical reactions and spectral data.