736-52-7Relevant academic research and scientific papers
Tricarbonyl 99mTc(i) and Re(i)-thiosemicarbazone complexes: synthesis, characterization and biological evaluation for targeting bacterial infection
Nayak, Dipak Kumar,Baishya, Rinku,Natarajan, Ramalingam,Sen, Tuhinadri,Debnath, Mita Chatterjee
, p. 16136 - 16148 (2015)
Methyl, ethyl and phenyl nitrofuryl thiosemicarbazone ligands (1, 2 and 3 respectively) were radiolabeled with freshly prepared aqueous solution of a fac[99mTc(CO)3(H2O)3]+ precursor. The radiochemica
Synthesis and evaluation of thiosemicarbazones functionalized with furyl moieties as new chemosensors for anion recognition
Santos-Figueroa, Luis E.,Moragues, María E.,Raposo, M. Manuela M.,Batista, Rosa M. F.,Costa, Susana P. G.,Ferreira, R. Cristina M.,Sancenón, Félix,Martínez-Má?ez, Ramón,Ros-Lis, José Vicente,Soto, Juan
experimental part, p. 7418 - 7428 (2012/09/25)
A family of heterocyclic thiosemicarbazone dyes (3a-f and 4) containing furyl groups was synthesized in good yields, characterized and their response in acetonitrile in the presence of selected anions was studied. Acetonitrile solutions of 3a-f and 4 show
5-Nitrofuran-2-yl derivatives: Synthesis and inhibitory activities against growing and dormant mycobacterium species
Sriram, Dharmarajan,Yogeeswari, Perumal,Dhakla, Prathiba,Senthilkumar, Palaniappan,Banerjee, Debjani,Manjashetty, Thimmappa H.
body text, p. 1152 - 1154 (2009/08/07)
Eighteen 5-nitrofuran-2-yl derivatives were prepared by reacting 5-nitro-2-furfural with various (sub)phenyl/pyridyl thiosemicarbazide using microwave irradiation. The compounds were tested for their in vitro activity against tubercular and various non-tubercular mycobacterium species in log-phase and 6-week-starved cultures. Compound N-(3,5-dibromopyridin-2-yl)-2-((5-nitrofuran-2-yl)methylene)hydrazinecarbothioamide (4r) was found to be the most potent compound (MIC: 0.22 μM) and was 3 times more active than standard isoniazid (INH) and equally active as rifampicin (RIF) in log-phase culture of Mycobacterium tuberculosis H37Rv. In starved M. tuberculosis H37Rv, 4r inhibited with MIC of 13.9 μM and was found to be 50 times more active than INH and slightly more active than RIF.
Synthesis and antimicrobial activity of some 2,5-disubstituted 1,3,4-thiadiazole derivatives
Mamolo,Vio,Banfi
, p. 71 - 74 (2007/10/03)
A series of 5-substituted 2-arylamino-1,3,4-thiadiazole derivatives was prepared. The antimicrobial activity of these compounds against some strains of bacteria and a strain of Candida albicans was determined, together with that of the corresponding thiosemicarbazone derivatives, which are intermediates in the synthetical procedure.
