73604-52-1

Usage

Uses

Used in Pharmaceutical Industry:
2,4,4-Trimethyl-pyrrolidine is used as a solvent for the synthesis of various pharmaceutical compounds, facilitating the production of medications that address a range of health conditions.
Used in Pesticide Industry:
In the pesticide sector, 2,4,4-Trimethyl-pyrrolidine serves as a solvent, aiding in the formulation of effective pest control products that protect crops and enhance agricultural productivity.
Used in Polymer Industry:
2,4,4-Trimethyl-pyrrolidine is utilized as a solvent in the manufacturing of polymers, contributing to the development of materials with diverse applications in industries such as plastics, textiles, and coatings.
Used as a Corrosion Inhibitor:
2,4,4-Trimethyl-pyrrolidine is employed as a corrosion inhibitor, protecting metal surfaces from degradation and extending the lifespan of equipment and structures in various industries.
Used in Dye and Pigment Production:
This chemical compound is used in the production of dyes and pigments, contributing to the creation of vibrant colors and hues for use in textiles, paints, and other applications.

Upstream product

• 2045-75-2 3,3,5-trimethyl-3,4-dihydro-2H-pyrrole 
• 73604-46-3 2,2-dimethyl-1-amino-pent-4-ene 
• 2978-30-5 2,2-dimethylpent-4-enenitrile 
• 6931-11-9 2,4,4-trimethyl-1-pyrroline N-oxide 
• 7647-01-0 hydrogenchloride 
• 35223-73-5 4,4-dimethyl-5-nitropentan-2-one 
• 101861-91-0 4,4-ethylenedioxy-2,2-dimethyl-1-nitropentane 
• 54408-36-5 2,4,4-trimethylpyrrolidine-1-ol 

Relevant academic research and scientific papers

Investigating a Redox Active Samarium Complex in Catalytic Reactions

Herein the synthesis of a new ethynyl ferrocenyl amidinate ligand [Fc?C≡C-{C(Ndipp)2H}] (Fc=ferrocenyl; dipp=diisopropylphenyl) and the subsequent formation of the corresponding samarium amido complex [Sm{Fc?C≡C-[C(Ndipp)2]}2/s

Carbon—carbon and carbon—nitrogen bond formation reactions catalyzed by the magnesium and calcium acenaphthene-1,2-diimine complexes

A mixture of allylbromide and diphenylacetonitrile is reduced to afford 2,2-diphenylpentene-4-nitrile as a major product in the presence of catalytic amounts of the magnesium complex (dpp-bian)Mg(thf)3 (dpp-bian is 1,2-bis[(2,6-diisopropylphenyl)imino]acenaphthene dianion). The overall conversion of nitrile is 71% within 3 h at 85 °С. 4,4-Diphenylbutene-1 and diphenylmethane are by-products in this process. Complexes (dpp-bian)Mg(thf)3 and (dpp-bian)Ca(thf)4 (in an amount of 0.5—5 mol.%) catalyze the intramolecular hydroamination of some aminopentenes and aminohexenes with the conversion from 67 to 99%.

Bora-amidinate as a cooperative ligand in group 2 metal catalysis

Syntheses and crystal structures of the monomeric bora-amidinate (bam) complexes DIPPNBN-Mg·(THF)3 and DIPPNBN-Ca·(THF)4 are presented; DIPPNBN = HB[N(2,6-iPr2-C6H3)]

Bis(amidinate) ligands in early lanthanide chemistry - synthesis, structures, and hydroamination catalysis

Bis(amidinate) ligands attached to rigid dibenzofuran and phenanthrene backbones have been introduced into lanthanide chemistry for the first time. Depending on the ligand and on the lanthanide source, either bi- and tetra-metallic macrocycles or monometa

Cyclopentadienyl-based Mg complexes in the intramolecular hydroamination of aminoalkenes: Mechanistic evidence for cationic: Versus neutral magnesium derivatives

Neutral and cationic magnesium complexes stabilized by coordination of a cyclopentadienyl ligand with two different neutral hemilabile donor groups [Mg{η5-C5H3-1,3-(CH2CH2NiPr2)(SiMe2NPh2)}X(thf)] (X = Bz (2); N(SiMe3)2 (3)) and [Mg{η5-C5H3-1,3-(CH2CH2NiPr2)(SiMe2NPh2)}][BPh4] (4) have been prepared and characterized. The 1H-13C HMBC and HSQC spectra of compounds 2 and 3 demonstrate the formation of 1,3-substituted cyclopentadienyl compounds and DOSY and 1H-NMR experiments support the coordination-decoordination in solution of a THF molecule in complex 2. No Schlenk-type ligand redistributions were observed in the chemical behaviour of these magnesium complexes. Compounds 2-4 are active catalysts in the hydroamination of aminoalkenes; stoichiometric reactions and kinetic measurements have been performed to gain an insight into their reaction mechanisms. A key contribution here is the catalytic reactivity of a cationic magnesium compound.

CCC-NHC Pincer Zr Diamido Complexes: Synthesis, Characterisation, and Catalytic Activity in Hydroamination/Cyclisation of Unactivated Amino-Alkenes,-Alkynes, and Allenes

2-(1,3-Bis-3′-butylimidazol-1′-yl-2′-ylidene)phenylene)bis(dimethylamido) iodo zirconium(iv) (3) and 2-(1,3-bis-3′-butylimidazol-1′-yl-2′-ylidene)phenylene)bis (dimethylamido) bromo zirconium(iv) (4), have been prepared via a modification of the solvent and stoichiometry from the previously reported methodology. The reactivity of 3 and 4 in hydroamination/cyclisation is reported. Both diamido complexes have been found to improve catalytic activity as compared with the previously reported mono-amido analogues. Complexes 3 and 4 were observed to be selective for primary amines over secondary amines in hydroamination/cyclisation. The lack of reactivity with secondary amines is consistent with a mechanism involving requisite formation of a Zr-imido intermediate.

Rare-earth metal diisopropylamide-catalyzed intramolecular hydroamination

Rare-earth metal diisopropylamide complexes LiLn(NiPr2)4(THF) (Ln = Sc, Y, La), [LiY(NiPr2)4]n, NaLn(NiPr2)4(THF) (Ln = Sc, Y), Sc(NiPr2)3(THF) and Ce(NiPr

Novel yttrium and zirconium catalysts featuring reduced Ar-BIANH2 ligands for olefin hydroamination (Ar-BIANH2 = bis-arylaminoacenaphthylene)

The novel class of bis-arylaminoacenaphthylenes (Ar-BIANH2) was employed for the preparation of zirconium and yttrium complexes to be used as catalysts for cyclohydroamination of a number of primary and secondary aminoalkenes. The complex [(2,6

Highly fluorinated tris(indazolyl)borate silylamido complexes of the heavier alkaline earth metals: Synthesis, characterization, and efficient catalytic intramolecular hydroamination

Heteroleptic silylamido complexes of the heavier alkaline earth elements calcium and strontium containing the highly fluorinated 3-phenyl hydrotris(indazolyl)borate {F12-Tp4Bo,3Ph}- ligand have been synthesized by using salt metathesis reactions. The homoleptic precursors [Ae{N-(SiMe3)2}2] (Ae=Ca, Sr) were treated with [Tl(F12-Tp4Bo,3Ph)] in pentane to form the corresponding heteroleptic complexes [(F12-Tp4Bo,3Ph)Ae{N(SiMe3)2}] (Ae=Ca (1); Sr (3)). Compounds 1 and 3 are inert towards intermolecular redistribution. The molecular structures of 1 and 3 have been determined by using X-ray diffraction. Compound 3 exhibits a Sr...MeSi agostic distortion. The synthesis of the homoleptic THF-free compound [Ca{N(SiMe2H)2}2] (4) by transamination reaction between [Ca{N(SiMe3)2}2] and HN(SiMe2H)2 is also reported. This precursor constitutes a convenient starting material for the subsequent preparation of the THF-free complex [(F12-Tp4Bo,3Ph)Ca{N(SiMe2H)2}] (5). Compound 5 is stabilized in the solid state by a Ca...β-Si-H agostic interaction. Complexes 1 and 3 have been used as precatalysts for the intramolecular hydroamination of 2,2-dimethylpent-4-en-1-amine. Compound 1 is highly active, converting completely 200 equivalents of aminoalkene in 16 min with 0.50 mol% catalyst loading at 25°C.

σ-Insertive mechanism versus concerted non-insertive mechanism in the intramolecular hydroamination of aminoalkenes catalyzed by phenoxyamine magnesium complexes: A synthetic and computational study

The phenoxyamine magnesium complexes [{ONN}MgCH2Ph] (4 a: {ONN}=2,4-tBu2-6-(CH2NMeCH2CH2NMe2)C6H2O-; 4 b: {ONN}=4-tBu-2-(CH2NMeCH2CHs