73606-41-4

Basic information

• Product Name: 2-Propynenitrile, 3-(2-thienyl)- (9CI)
• Synonyms: 2-Propynenitrile, 3-(2-thienyl)- (9CI)
• CAS NO: 73606-41-4
• Molecular Formula: C7H3NS
• Molecular Weight: 133.17042
• Mol File: 73606-41-4.mol
• Article Data: 7

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-Propynenitrile, 3-(2-thienyl)- (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Propynenitrile, 3-(2-thienyl)- (9CI)(73606-41-4)
• EPA Substance Registry System: 2-Propynenitrile, 3-(2-thienyl)- (9CI)(73606-41-4)

Safety Data

• Hazardous Substances Data: 73606-41-4(Hazardous Substances Data)

Upstream product

• 1194-13-4 3-thiophen-2-yl-prop-2-yn-1-ol 
• 4302-40-3 3-chloro-3-(thiophen-2-yl)acrylaldehyde 
• 88-15-3 2-Acetylthiophene 
• 1453164-36-7 2-(3-azidoprop-1-yn-1-yl)thiophene 
• 5271-67-0 2-Thiophenecarbonyl chloride 
• 98-03-3 thiophene-2-carbaldehyde 
• 545-06-2 trichloroacetonitrile 
• 5068-04-2 thien-2-oyl-cyanomethylenetriphenylphosphorane 

Relevant articles and documents

Enantioselective Nickel-Catalyzed Alkyne-Azide Cycloaddition by Dynamic Kinetic Resolution

The triazole heterocycle has been widely adopted as an isostere for the amide bond. Many native amides are α-chiral, being derived from amino acids. This makes α-N-chiral triazoles attractive building blocks. This report describes the first enantioselective triazole synthesis that proceeds via nickel-catalyzed alkyne-azide cycloaddition (NiAAC). This dynamic kinetic resolution is enabled by a spontaneous [3,3]-sigmatropic rearrangement of the allylic azide. The 1,4,5-trisubstituted triazole products, derived from internal alkynes, are complementary to those commonly obtained by the related CuAAC reaction. Initial mechanistic experiments indicate that the NiAAC reaction proceeds through a monometallic Ni complex, which is distinct from the CuAAC manifold.

MOLECULAR SOLAR ENERGY STORAGE

The present invention relates to norbornadiene compounds (Formula I), and the corresponding quadricyclane compounds (Formula III). The compounds are to be included in a molecular thermal systems (MOST), and to be used for storing solar energy.

Copper-catalyzed oxidative transformation of aryl propargylic azides to aryl propiolonitriles

A concise copper(I)-catalyzed oxidative transformation of aryl propargyl azides to aryl propiolonitriles has been developed. Aryl propiolonitrile derivatives can be obtained in moderate to good yields by this strategy. An oxidative Schmidt rearrangement is involved in this transformation. Copyright