736156-58-4

Upstream product

• 886580-13-8 (E)-4-(tert-butyldimethylsilyloxy)-3-phenylbut-2-enoic acid methyl ester 
• 103548-04-5 2-(tert-butyldimethylsilanyloxy)-1-phenylethan-1-one 
• 940292-97-7 2,3-dibromo-4-(tert-butyl-dimethyl-silanyloxy)-3-phenyl-butyric acid ethyl ester 
• 940292-95-5 (Z)-4-(t-butyldimethylsilyloxy)-3-phenyl-but-2-enoic acid ethyl ester 
• 940292-98-8 (E)-2-bromo-4-(tert-butyl-dimethyl-silanyloxy)-3-phenyl-but-2-enoic acid ethyl ester 
• 886580-17-2 (E)-2-bromo-4-(tert-butyldimethylsilyloxy)-3-phenylbut-2-enoic acid methyl ester 

Downstream Products

• 940293-03-8 (E)-1-[2-bromo-4-(tert-butyldimethylsilanyloxy)-3-phenyl-but-2-enyl]-5-iodouracil 
• 940293-02-7 (E)-1-[2-bromo-4-(tert-butyldimethylsilanyloxy)-3-phenyl-but-2-enyl]-5-fluorouracil 
• 940293-05-0 (E)-9-[2-bromo-4-(tert-butyldimethylsilanyloxy)-3-phenyl-but-2-enyl]-adenine 
• 940293-00-5 (E)-1-[2-bromo-4-(tert-butyldimethylsilanyloxy)-3-phenyl-but-2-enyl]thymine 
• 940293-01-6 (E)-1-[2-bromo-4-(tert-butyldimethylsilanyloxy)-3-phenyl-but-2-enyl]uracil 
• 940293-04-9 (E)-1-[2-bromo-4-(tert-butyldimethylsilanyloxy)-3-phenyl-but-2-enyl]-cytosine 
• 940292-99-9 (E)-tert-butyl-(3,4-dibromo-2-phenyl-but-2-enyloxy)-dimethylsilane 

Relevant academic research and scientific papers

Synthesis and DNA cleavage reaction characteristics of enediyne prodrugs activated via an allylic rearrangement by base or UV irradiation

A number of enediyne prodrugs 1-5 possessing an (E)-3-hydroxy-4-(2′- hydroxy-1′-phenylethylidene)cyclodeca-1,5-diyne scaffold have been synthesized via the Sonogashira coupling and an intramolecular Nozaki-Hiyama-Kishi reaction as the key steps. Upon incu

Simple synthesis of novel acyclic (E)-bromovinyl nucleosides as potential antiviral agents

In these study, novel acyclic (E)-bromovinyl nucleosides were synthesized as potential antiviral agents. The coupling of the allylic bromide 9 with bases (thymine, uracil, 5-fluorouracul, 5-iodouracil, cytosine, adenine) afforded a series of novel acyclic