73625-11-3Relevant academic research and scientific papers
ERGOLINE-LIKE COMPOUNDS FOR PROMOTING NEURAL PLASTICITY
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Paragraph 0275, (2021/04/23)
Provided herein are ergoline-derived heterocyclic compounds which can be useful for methods of treating a disease or for increasing neural plasticity. The compounds can also be useful for increasing dendritic spine density.
Bicyclic and tricyclic ergoline partial structures: Rigid 3-(2-aminoethyl)pyrroles and 3- and 4-(2-aminoethyl)pyrazoles as dopamine agonists
Bach,Kornfeld,Jones,Chaney,Dorman,Paschal,Clemens,Smalstig
, p. 481 - 491 (2007/10/02)
It is proposed, based upon comparisons with apomorphine, that the rigid pyrroleethylamine moiety of the ergolines is the portion of the molecule responsible for dopamine agonist activity. In support of this hypothesis, bicyclic and tricyclic ergoline part
