7364-48-9Relevant academic research and scientific papers
Preparation, isolation, and characterization of Nα-Fmoc- peptide isocyanates: Solution synthesis of oligo-α-peptidyl ureas
Sureshbabu, Vommina V.,Patil, Basanagoud S.,Venkataramanarao, Rao
, p. 7697 - 7705 (2007/10/03)
(Chemical Equation Presented) The Nα-Fmoc-peptide isocyanates 3a-q, 4a-c, and 5a-c were prepared by the Curtius rearrangement of Nα-Fmoc-peptide acid azides in toluene under thermal, microwave, and ultrasonic conditions. All the Nsu
Synthesis of a novel ester analog of nucleic acids bearing a serine backbone
Murata, Asako,Wada, Takeshi
, p. 2933 - 2936 (2007/10/03)
A novel analog of nucleic acids bearing an optically active serine ester backbone, serine-based nucleobase-linked polyester (SNE), was synthesized. Monomers containing a thymine base were synthesized from l- and d-serines. Furthermore, reaction conditions
Isocyanates of Nα-[(9-fluorenylmethyl)oxy]carbonyl amino acids: Synthesis, isolation, characterization, and application to the efficient synthesis of urea peptidomimetics
Patil, Basanagoud S.,Vasanthakumar, Ganga-Ramu,Suresh Babu, Vommina V.
, p. 7274 - 7280 (2007/10/03)
The Curtius rearrangement of Fmoc-amino acid azides 1 was carried out in toluene by refluxing the solution for 30 min. The resulting isocyanates 2 have been isolated as crystalline solids and are fully characterized by IR, 1H NMR, 13
Surrogates for Chiral Aminomalondialdehyde. Synthesis of N-(9-Phenylfluoren-9-yl)serinal and N-(9-Phenylfluoren-9-yl)vinylglycinal
Lubell, William,Rapoport, Henry
, p. 3824 - 3831 (2007/10/02)
The cyclic carbamate of N-(9-phenylfluoren-9-yl)serinal (5) and N-(9-phenylfluoren-9-yl)aminomalondialdehyde mono(dimethyl acetal) (16) were prepared from L-serine.Exposure to silica and nonnucleophilic base and treatment in Wittig coupling reactions proc
Efficient "One-Pot" Synthesis of N-Trityl Amino Acids
Barlos, Kleomenis,Papaioannou, Dionysios,Theodoropoulos, Dimitrios
, p. 1324 - 1326 (2007/10/02)
A sequential procedure has been developed whereby neutral amino acids 1 were tritylated via their corresponding trimethylsilyl esters 2 to afford, after mild hydrolysis, N-trityl amino acids 3 in high yields and purity.Hydroxy amino acids 4 were preferent
