73647-07-1Relevant academic research and scientific papers
Bis(dimethylamino)phosphorodiamidate: A Reagent for the Regioselective Cyclophosphorylation of cis-Diols Enabling One-Step Access to High-Value Target Cyclophosphates
Yadav, Mahipal,Krishnamurthy, Ramanarayanan
, p. 7400 - 7404 (2019)
Bis(dimethylamino)phosphorodiamidate (BDMDAP) enables an efficient and one-pot cyclophosphorylation of vicinal cis-diol moiety of polyol-organics of biological importance without the need for protecting group chemistry and is amenable to large-scale reactions. The utility of this reagent is demonstrated through the synthesis of high-value targets such as cyclic phosphates of myo-inositol, nucleosides, metabolites, and drug molecules.
Direct Transformation of Ribonucleoside Cyclic 3',5'-Phosphorothioates into Cyclic 2',3'-Phosphates
Okruszek, Andrzej,Guga, Piotr,Stec, Wojciech J.
, p. 1225 - 1226 (2007/10/02)
Ribonucleoside cyclic 3',5'-phosphorothioates react with oxiranes to give preferentially ribonucleoside cyclic 2',3'-phosphates.
