73661-48-0

Basic information

• Product Name: oxime 2,6,6-trimethylcyclohex-1-ene-1-carbaldehyde
• Synonyms: oxime 2,6,6-trimethylcyclohex-1-ene-1-carbaldehyde
• CAS NO: 73661-48-0
• Molecular Weight: 167.251
• Mol File: 73661-48-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: oxime 2,6,6-trimethylcyclohex-1-ene-1-carbaldehyde(CAS DataBase Reference)
• NIST Chemistry Reference: oxime 2,6,6-trimethylcyclohex-1-ene-1-carbaldehyde(73661-48-0)
• EPA Substance Registry System: oxime 2,6,6-trimethylcyclohex-1-ene-1-carbaldehyde(73661-48-0)

Safety Data

• Hazardous Substances Data: 73661-48-0(Hazardous Substances Data)

Upstream product

• 432-25-7 2,6,6-trimethylcyclohex-1-enecarbaldehyde 

Downstream Products

• 72152-84-2 2,6,6-trimethylcyclohexa-1,3-dienecarbonitrile 
• 19203-43-1 (2,6,6-Trimethylcyclohexenyl)nitriloxid 
• 57524-14-8 2,2,6-trimethyl-1-cyclohexenylcarbonitrile 
• 19206-30-5 1,1,3-Trimethyl-cyclohexen-⁽¹⁾-yl-⁽²⁾-N¹-phenyl-N²-hydroxy-formamidin 
• 19206-34-9 N-<2,6,6-Trimethyl-cyclohexen-(1)-yl>-N'-phenyl-harnstoff 
• 19206-32-7 N-<2,6,6-Trimethyl-cyclohexen-(1)-yl-carbonyl>-hydroxylamin 
• 19221-86-4 5-phenyl-3-(2,6,6-trimethyl-cyclohex-1-enyl)-isoxazole 
• 19206-28-1 5-amino-3-(2,6,6-trimethyl-cyclohex-1-enyl)-isoxazole-4-carbonitrile 
• 432-25-7 2,6,6-trimethylcyclohex-1-enecarbaldehyde 

Relevant articles and documents

Synthesis of nitrogen-containing monoterpenoids with antibacterial activity

Incorporation of the Beckmann rearrangement into the presented research resulted in the formation of nitrogen-containing terpenoid derivatives originating from naturally occurring compounds. Both starting monoterpenes and obtained derivatives were subjected to estimation of their antibacterial potential. In the presented study, Staphylococcus aureus was the most sensitive to examined compounds. The Minimal Inhibitory Concentration (MIC) experiments performed on S. aureus demonstrated that the (?)-menthone oxime (?)-8 and (+)-pulegone oxime (+)-13 had the best antibacterial activity among the tested derivatives and starting compounds. Their MIC90 value was 100 μg/mL. The obtained derivatives were also evaluated for their inhibitory activity against bacterial urease. Among the tested compounds, three active inhibitors were found–oxime 14 and lactams (?)-15 and 16 limited the activity of Sporosarcina pasteurii urease with Ki values of 174.3 μM, 43.0 μM and 4.6 μM, respectively. To our knowledge, derivative 16 is the most active antiureolytic lactam described to date.