73669-78-0Relevant academic research and scientific papers
Direct asymmetric Michael addition of ketones to chalcones catalyzed by a hydroxyphthalimide derived triazole-pyrrolidine
Kumar, Togapur Pavan,Sattar, Mohammad Abdul,Sarma, Vanka Uma Maheshwara
, p. 1615 - 1619 (2014/01/06)
An efficient protocol for the enantioselective Michael additions of ketones to chalcones catalyzed by a hydroxyphthalimide linked triazole-pyrrolidine derivative has been developed. The corresponding products, 1,5-dicarbonyl compounds, were obtained in good yields with high levels of stereoselectivities under mild reaction conditions employing benzoic acid as an additive.
Three-step synthesis of 2,4-diaryl-5,6,7,8-tetrahydroquinoline derivatives
Gezegen, Hayreddin,Dingil, Alparslan,Ceylan, Mustafa
experimental part, p. 1017 - 1024 (2010/10/21)
(Chemical Equation Presented) Addition of cylohexanone to chalcones, obtained from the appropriate acetophenone and benzaldehyde derivatives, under solvent-free conditions gave 1,5-diketones in good yields. Treatment of 1,5-diketones with ammonium acetate in acetic acid afforded directly 2,4-diaryl-5,6,7,8-tetrahydroquinoline derivatives (7a-u) in high yields. The structures of 7a-u were elucidated by 1H NMR, 13C NMR, IR, and elemental analysis.
