73671-65-5Relevant academic research and scientific papers
Azolyl methyl phenyl derivatives having aromatase inhibitory activity
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, (2008/06/13)
Compounds exerting excellent aromatase inhibitory activity in vivo and in vitro with higher specificity and greater safety are provided together with the salts thereof. Using the same, there are also provided, prophylactic agents and/or therapeutical agents of estrogen-dependent diseases, contraceptive agents for females, and aromatase inhibitory agents for use in the form of reagents for human or animals. The compounds are of the formula (I), wherein R2 is represented by the formula (II) or (III). (I) (II) or
N-Benzyl-imidazoles as selective inhibitors of the thromboxane synthetase enzyme
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, (2008/06/13)
The N-(substituted benzyl) imidazoles are selective enzyme inhibitors and thus are useful in the treatment of heart disease, circulatory and vascular problems.
