54828-00-1

Basic information

• Product Name: 4-chloro-2-[(dimethylamino)methyl]phenol
• Synonyms: 4-Chloro-2-[(dimethylamino)methyl]phenol; 4-Chloro-a-(dimethylamino)-O-cresol; Phenol, 4-chloro-2-[(dimethylamino)methyl]-
• CAS NO: 54828-00-1
• Molecular Formula: C₉H₁₂ClNO
• Molecular Weight: 185.6507
• Mol File: 54828-00-1.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 250.6°C at 760 mmHg
• Flash Point: 105.4°C
• Density: 1.187g/cm³
• Vapor Pressure: 0.0135mmHg at 25°C
• Refractive Index: 1.564
• CAS DataBase Reference: 4-chloro-2-[(dimethylamino)methyl]phenol(CAS DataBase Reference)
• NIST Chemistry Reference: 4-chloro-2-[(dimethylamino)methyl]phenol(54828-00-1)
• EPA Substance Registry System: 4-chloro-2-[(dimethylamino)methyl]phenol(54828-00-1)

Safety Data

• Hazardous Substances Data: 54828-00-1(Hazardous Substances Data)

Upstream product

• 51-80-9 bis-(dimethylamino)methane 
• 106-48-9 4-chloro-phenol 
• 70112-21-9 N,N-dimethyl-2-hydroxy-5-chlorobenzamide 
• 50-00-0 formaldehyd 
• 124-40-3 dimethyl amine 

Downstream Products

• 73671-65-5 4-chloro-2-(1H-imidazol-1-ylmethyl)phenol 
• 95062-48-9 4-chloro-1,2-quinodimethane 
• 100-02-7 4-nitro-phenol 
• 6296-65-7 1-(5-chloro-2-hydroxyphenyl)-N,N,N-trimethylmethanaminium iodide 
• 73779-25-6 2-(2-Benzenesulfonyl-ethyl)-4-chloro-phenol 

Relevant articles and documents

Convenient synthesis of 2-Amino-4H-chromenes from photochemically generated o-quinone methides and malononitrile

2-Amino-4H-chromenes were synthesized in moderate to good yields by the reaction of o-quinone methides photochemically generated from o-(dimethylaminomethyl)phenols with malononitrile. This method was applicable to the synthesis of fluorinated chromenes that were difficult to obtain by other methods. In addition, o-(hydroxymethyl)phenols could be used for the reaction in the presence of tertiary amine bases.

2-(aminoalkoxy) phenylalkylamines with antiinflammatory activity

Compounds of the formula I STR1 including pharmaceutically acceptable salts thereof are disclosed in which R1, R2, R3, and R4 independently represent hydrogen, hydroxy, halo, halogenated alkyl, halogenated alkox