73680-15-6Relevant articles and documents
Last of the gem-Difluorocycloalkanes: Synthesis and Characterization of 2,2-Difluorocyclobutyl-Substituted Building Blocks
Chernykh, Anton V.,Melnykov, Kostiantyn P.,Tolmacheva, Nataliya A.,Kondratov, Ivan S.,Radchenko, Dmytro S.,Daniliuc, Constantin G.,Volochnyuk, Dmitriy M.,Ryabukhin, Sergey V.,Kuchkovska, Yuliya O.,Grygorenko, Oleksandr O.
, p. 8487 - 8496 (2019/08/30)
An efficient approach to synthesis of previously unavailable 2-substituted difluorocyclobutane building blocks was developed and applied on a multigram scale. The key step of the synthetic sequence included deoxofluorination of O-protected 2-(hydroxylmeth
