736927-94-9Relevant academic research and scientific papers
Metal-free C-H arylation of imidazoheterocycles with aryl hydrazines
Jana, Sourav,Samanta, Sadhanendu,Bagdi, Avik K.,Shirinian, Valerii Z.,Hajra, Alakananda
, p. 12360 - 12367 (2018)
A simple and efficient metal-free arylation of imidazo[1,2-a]pyridines at the C-3 position with arylhydrazine has been achieved at room temperature under ambient air conditions. Various 2,3-disubstituted imidazopyridines and imidazothiazoles were synthesized with high yields. The present methodology demonstrates the usefulness of commercially available aryl hydrazine as an arylating agent.
A novel pathway to imidazo[1,2-a]pyridines. Access through imino pyridinium salts
Neue, Benedikt,Froehlich, Roland,Wuerthwein, Emst-Ulrich
, p. 295 - 304 (2012/07/14)
A new synthetic strategy for the preparation of imidazo[1,2-a]pyridines 10 is reported, which is based on the electrocyclization reaction of imino pyridinium salts 7 upon treatment with a strong base. The starting materials are easily prepared from 2-amin
