73709-51-0Relevant academic research and scientific papers
α-Xanthylmethyl Ketones from α-Diazo ketones
López-Mendoza, Pedro,Miranda, Luis D.
, p. 3777 - 3790 (2021/07/07)
A simple and efficient method to obtain α-xanthylmethyl ketones from α-diazo ketones is described. The reaction proceeds through a protonation/nucleophilic substitution sequence in the presence of p -toluenesulfonic acid and potassium ethyl xanthogenate as the nucleophile. As α-diazo ketones can be readily synthesized from ubiquitous carboxylic acids, a broad variety of xanthates can be obtained, including examples from naturally occurring substrates.
