73734-68-6 Usage
Molecular structure
1H-Benzimidazol-2-amine, N-[1-(1-phenylethyl)-4-piperidinyl]-1-(phenylmethyl)is a complex organic compound that consists of a benzimidazole ring, an amine group, a piperidine ring, and a phenylmethyl group.
Potential as a ligand
1H-Benzimidazol-2-amine,
N-[1-(1-phenylethyl)-4-piperidinyl]-1-(phenylmethyl)- has the potential to bind to various receptors and enzymes, which could have implications in the central nervous system.
Biological activity
While further research is needed, 1H-Benzimidazol-2-amine,
N-[1-(1-phenylethyl)-4-piperidinyl]-1-(phenylmethyl)- may have biological activity in the central nervous system.
Applications in drug design
Due to its potential as a ligand and biological activity, 1H-Benzimidazol-2-amine,
N-[1-(1-phenylethyl)-4-piperidinyl]-1-(phenylmethyl)- could have applications in drug design and development, particularly in the fields of neuroscience and pharmacology.
Need for further research
While 1H-Benzimidazol-2-amine,
N-[1-(1-phenylethyl)-4-piperidinyl]-1-(phenylmethyl)- shows promise, more research is needed to fully understand its properties and potential uses.
Check Digit Verification of cas no
The CAS Registry Mumber 73734-68-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,3,7,3 and 4 respectively; the second part has 2 digits, 6 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 73734-68:
(7*7)+(6*3)+(5*7)+(4*3)+(3*4)+(2*6)+(1*8)=146
146 % 10 = 6
So 73734-68-6 is a valid CAS Registry Number.
73734-68-6Relevant academic research and scientific papers
New antihistaminic N-heterocyclic 4-piperidinamines. 1. Synthesis and antihistaminic activity of N-(4-piperidinyl)-1H-benzimidazol-2-amines
Janssens,Torremans,Janssen,Stokbroekx,Luyckx
, p. 1925 - 1933 (2007/10/02)
The synthesis of a series N-(4-piperidinyl)-1H-benzimidazol-2-amines and the preliminary evaluation of their in vitro and in vivo antihistaminic activity are described. Cyclodesulfurization of (2-aminophenyl) thioureas with mercury(II) oxide resulted in 2-aminobenzimidazole intermediates, which were monoalkylated on the endo-nitrogen atom. After deprotection of the piperideine nitrogen atom with 48% aqueous hydrobromic acid solution, the title compounds were obtained by three different methods, viz. alkylation, reductive amination, or oxirane ring-opening reactions. The in vivo antihistaminic activity was evaluated by the compound 48/80 induced lethality test in rats and histamine-induced lethality test in guinea pigs after oral and/or subcutaneous administration. The duration of action, for a selected number of compounds, was studied in the guinea pig. The phenylethyl derivatives showed the most potent antihistamine properties after oral administration in both animal species.
