73753-98-7

Upstream product

• 85-44-9 phthalic anhydride 
• 119-26-6 (2,4-dinitro-phenyl)-hydrazine 
• 4870-16-0 N-anilinophthalimide 
• 100-63-0 phenylhydrazine 
• 88-95-9 Phthaloyl dichloride 
• 97-00-7 1-chloro-2,4-dinitro-benzene 
• 88-99-3 benzene-1,2-dicarboxylic acid 
• 95980-68-0 phthalic acid mono-[N'-(2,4-dinitro-phenyl)-hydrazide] 
• 69793-63-1 2-(2,4-dinitrophenyl)-1,4-phthalazinedione 

Downstream Products

• 100621-23-6 2,4-diaminophenylaminophthalimide 
• 95980-68-0 phthalic acid mono-[N'-(2,4-dinitro-phenyl)-hydrazide] 
• 69793-63-1 2-(2,4-dinitrophenyl)-1,4-phthalazinedione 
• 107525-79-1 2-(2,4-bis-acetylamino-anilino)-isoindoline-1,3-dione 

Relevant academic research and scientific papers

Synthesis, X-ray, 1H-NMR and DFT analysis of the phthalimide–hydrazone probes as selective anion sensor

Two simple phthalimide–hydrazone probes with nitro groups were synthesised and characterised by NMR, FT-IR, HR-MS and single crystal X-ray crystallography. The synthesised receptors were evaluated for application in anion sensing. The receptors displayed strong, sensitive and selective colouration in the presence of cyanide ions by forming a stable complex with cyanide ion. The use of variable nitro groups helped in the elucidation of the mechanism of the complex formation. The 1H NMR spectroscopy was used to support the mechanism of the complex formation. DFT methods were used to understand the stability of the complex with respect to the reactant. The absorbance data were also compared with the TD-DFT calculated excitation parameters. The experimental results were found to correlate well with the theoretical data.

Preparation of the N-substituted 1,4-phthalazinedione derivatives

Preparation of 1,4-phthalazinedione derivatives from N-aminophthalimide derivatives by condensation of phthalic anhydride with arylhydrazines or isomerization of N-aminophthalimides is described.

Process for the production of cyclic carboxylic acid imides

In a process for reacting an aromatic or hydroaromatic alicyclic or heterocyclic dicarboxylic acid or its anhydride with an aliphatic or aromatic alicyclic or heterocyclic mono- or di-amine to produce an N-substituted dicarboxylic acid imide with a splitting off of water, the improvement of carrying out the reaction in a liquid solvent mixture consisting essentially of a non-polar organic solvent and a strongly polar organic solvent which together form a ternary azeotrope with water at reaction temperatures between about 40°C. and 160°C. The imide products are generally known for use as intermediates and final products in a number of industries.