73771-11-6

Usage

Uses

Used in Organic Chemistry Research:
4-Chloro-Pyridine-2-Carboxylic Acid Hydrazide is used as a reagent in various chemical reactions, contributing to the synthesis of new compounds and the exploration of reaction mechanisms. Its unique structure allows for versatile applications in the development of novel organic molecules.
Used in Pharmaceutical Development:
In the pharmaceutical industry, 4-Chloro-Pyridine-2-Carboxylic Acid Hydrazide is used as a key intermediate in the synthesis of potential drug candidates. Its presence in the molecular structure can influence the biological activity and pharmacological properties of the final drug product, making it a valuable component in the design and synthesis of new therapeutic agents.
Used in Material Science:
4-Chloro-Pyridine-2-Carboxylic Acid Hydrazide is employed in the development of new materials with specific properties, such as improved stability or reactivity. Its incorporation into the molecular structure of these materials can lead to enhanced performance in various applications, including catalysis, sensors, and advanced materials for energy storage or conversion.

InChI:InChI=1/C6H6ClN3O/c7-4-1-2-9-5(3-4)6(11)10-8/h1-3H,8H2,(H,10,11)

Upstream product

• 53750-66-6 4-chloro-pyridine-2-carbonyl chloride 
• 636-80-6 2-picolinic acid hydrochloride 
• 176977-85-8 methyl 4-chloropyridine-2-carboxylate hydrochloride 
• 24484-93-3 4-Chloro-pyridine-2-carboxylic acid methyl ester 

Downstream Products

• 19798-80-2 2-Amino-4-chloropyridine 
• 284462-37-9 4-(4-aminophenoxy)-N-methylpyridine-2-carboxamide 

Relevant academic research and scientific papers

Pyridine acylhydrazone compound as well as synthetic method and application thereof

The invention relates to a pyridine acylhydrazone compound as well as a synthetic method and application thereof. The structure of the compound is formula (shown in the description), wherein R represents halogen. The invention provides the pyridine acylhy

SUBSTITUTED PYRIDINE COMPOUNDS AS CRAC MODULATORS

The present invention relates to compounds described herein Formula (I) and pharmaceutical acceptable salts thereof, which modulate the activity of calcium release- activated calcium (CRAC) channel. The invention also describes the compounds of Formula (I)and pharmaceutical compositions containing such compounds thereof for treating, managing, and/or lessening the severity of diseases, disorders, syndromes or conditions associated with the modulation of calcium release-activated calcium (CRAC) channel.

NOVEL SUBSTITUTED PYRIDINYLOXY AND PYRIMIDINYLOXY AMIDES USEFUL AS INHIBITORS OF PROTEIN KINASES

The present invention relates to compounds and methods useful as inhibitors of protein kinases, including B-Raf and several receptor tyrosine and cytoplasmic tyrosine kinases. The present invention is directed to new substituted pyrimidinyloxy urea compounds of Formulas II, III and IV and compositions and their application as pharmaceuticals for the treatment of disease. Methods of modulating of protein kinase activity in a human or animal subject are also provided for the treatment diseases such as cancers.

NOVEL SUBSTITUTED PYRIMIDINYLOXY UREAS USEFUL AS INHIBITORS OF PROTEIN KINASES

The present invention relates to compounds and methods useful as inhibitors of protein kinases, including B-Raf and several receptor tyrosine and cytoplasmic tyrosine kinases. The present invention is directed to new substituted pyrimidinyloxy urea compounds of Formulas II, III and IV and compositions and their application as pharmaceuticals for the treatment of disease. Methods of modulating of protein kinase activity in a human or animal subject are also provided for the treatment diseases such as cancers.

Substituted 2-aminopyridines as inhibitors of nitric oxide synthase

Substituted 2-aminopyridine compounds of Formula (I) and pharmaceutically acceptable salts which have been found useful in the treatment of nitric oxide synthase mediated diseases and disorders. STR1

An improved large scale synthesis of 2-amino-4-chloropyridine and its use for the convenient preparation of various polychlorinated 2-aminopyridines

An efficient large scale synthesis of 2-amino-4-chloropyridine (3) has been achieved through a modification of existing literature procedures. Compound 3 was used to prepare the previously unreported 2-amino-4,5-dichloropyridine (4). The known 2-amino-3,4-dichloropyridine (5) and 2-amino-3,4,5-trichloropyridine (6) were pepared from 3 by new routes and in higher yields than previously reported.