737765-82-1Relevant academic research and scientific papers
Iridium-catalyzed intramolecular C–N and C–O/S cross-coupling reactions: Preparation of benzoazole derivatives
Shi, Yajie,Zhou, Qifan,Du, Fangyu,Fu, Yang,Du, Yang,Fang, Ting,Chen, Guoliang
, (2019/09/10)
The irdium-catalyzed intramolecular arylcarbon-hetero cross-coupling reactions with o-haloarylamides or o-haloarylamidine have been effectively achieved using KOAc and just 1 mol% catalyst. The [Ir(cod)Cl]2 was proved to be more potential for smoothly assembling functional structures benzimidazoles, benzoxazoles and benzothiazoles, which was superior to Cu- and Pd-catalyzed systems. Simultaneously, a concise and efficient synthesis of tafamidis was developed in 5-g scale.
Extended ethidium bromide analogue as a triple helix intercalator: Synthesis, photophysical properties and nucleic acids binding
Tam, Victor K.,Liu, Qi,Tor, Yitzhak
, p. 2684 - 2686 (2008/09/21)
Ethidium bromide has been extended by fusing an additional aromatic ring resulting in a larger intercalator with increased affinity for poly r(A)·r(U), poly d(A)·d(T) and triple helices when compared to the parent heterocycle. The Royal Society of Chemist
