73777-65-8

Usage

Uses

Used in Pharmaceutical Industry:
Renierone is used as a pharmaceutical compound for its potential therapeutic properties. Its unique structure and alkaloid nature make it a promising candidate for the development of new drugs and treatments.
Used in Chemical Research:
Renierone is used as a research compound in the field of organic chemistry. Its unique structure and properties allow scientists to study and understand the chemical behavior of alkaloids and their potential applications in various fields.
Used in Natural Product Extraction:
Renierone is used in the extraction and purification of natural products from marine sources. Its presence in the Reniera species sponge makes it a valuable resource for the discovery and development of new bioactive compounds with potential applications in various industries.

InChI:InChI=1/C17H17NO5/c1-5-9(2)17(21)23-8-12-13-11(6-7-18-12)14(19)10(3)16(22-4)15(13)20/h5-7H,8H2,1-4H3/b9-5+

Upstream product

• 79664-57-6 N-formyl-1,2-dihydrorenierone 
• 77515-79-8 (5,7,8-trimethoxy-6-methyl-1-isoquinolyl)methyl angelate 
• 77515-75-4 5,7,8-Trimethoxy-6-methyl-3,4-dihydro-1H-isoquinoline-1,2-dicarboxylic acid 2-benzyl ester 1-methyl ester 
• 77515-74-3 [2-(2,4,5-Trimethoxy-3-methyl-phenyl)-ethyl]-carbamic acid benzyl ester 
• 77515-76-5 5,7,8-Trimethoxy-6-methyl-1,2,3,4-tetrahydro-isoquinoline-1-carboxylic acid methyl ester 
• 77515-80-1 (5-methoxy-6-methyl-7,8-dioxo-7,8-dihydro-1-isoquinolyl)methyl angelate 
• 77515-77-6 5,7,8-Trimethoxy-6-methyl-isoquinoline-1-carboxylic acid methyl ester 
• 77515-73-2 (2,4,5-trimethoxy-3-methylphenyl)acetonitrile 
• 77515-72-1 1-chloromethyl-2,4,5-trimethoxy-3-methylbenzene 
• 84018-46-2 2-(2,4,5-Trimethoxy-3-methylphenyl)ethylamine 
• 110828-13-2 2,2-dimethoxy-N-(2,3,5-trimethoxy-4-methylbenzyl)-N-tosylethylamine 
• 110828-15-4 N-benzoyl-1-cyano-5,7,8-trimethoxy-6-methyl-1,2-dihydroisoquinoline 
• 110828-14-3 5,7,8-trimethoxy-6-methyl-N-tosyl-1,2-dihydroisoquinoline 
• 94893-31-9 2,2-dimethoxy-N-(2,3,5-trimethoxy-4-methylbenzylidene)ethylamine 

Downstream Products

• 77515-81-2 (5,8-dihydro-7-hydroxy-6-methyl-5,8-dioxo-1-isoquinolinyl)methyl (2Z)-2-methyl-2-butenoate 

Relevant academic research and scientific papers

Syntheses of the antibiotic alkaloids renierone, mimocin, renierol, renierol acetate, renierol propionate, and 7-methoxy-1,6-dimethylisoquinoline-5, 8-dione

The total synthesis of renierone, mimocin, renierol, renierol acetate, renierol propionate, and 7-methoxy-1,6-dimethylisoquinoline-5,8-dione was successfully achieved by the regioselective oxidation of 5-oxygenated isoquinoline. The synthetic method of the 5-oxygenated isoquinoline is based on the thermal electrocyclic reaction of 1-azahexatriene system involving the benzene 1,2-bond.

Chemistry of renieramycins. Part 6: Transformation of renieramycin M into jorumycin and renieramycin J including oxidative degradation products, mimosamycin, renierone, and renierol acetate

The transformation of renieramycin M (1m) into renieramycin J (1j) and jorumycin (2) is presented along with the results of antiproliferative assay data. The chemical stability and the oxidative degradation of 2 and renieramycin E (1e) to generate simple isoquinoline alkaloids, such as mimosamycin (7), renierol acetate (12), and renierone (8) are also described.