7378-38-3Relevant articles and documents
Catalytic hydrogenation of esters. Development of an efficient catalyst and processes for synthesising (R)-1,2-propanediol and 2-(l-Menthoxy)ethanol
Kuriyama, Wataru,Matsumoto, Takaji,Ogata, Osamu,Ino, Yasunori,Aoki, Kunimori,Tanaka, Shigeru,Ishida, Kenya,Kobayashi, Tohru,Sayo, Noboru,Saito, Takao
experimental part, p. 166 - 171 (2012/05/20)
A ruthenium catalyst for the reduction of esters by hydrogenation has been developed. Processes for the hydrogenation of esters have also been developed for (R)-1,2-propanediol and 2-(l-menthoxy)ethanol. The catalyst shows good catalytic activity for the hydrogenation of esters in methanol. Methyl lactate was reduced at 30 °C and gave turnover numbers (TON) up to 4000. The optical purity of the (R)-1,2-propanediol made by the hydrogenation of methyl (R)-lactate was higher than that via the asymmetric hydrogenation of hydroxyacetone. A hydrogenation process to replace the lithium aluminum hydride (LAH) reduction used in the production of 2-(l-menthoxy)ethanol was developed.
Synthesis of chiral O-functionalized isobornyloxy, menthyloxy and fenchyloxy cyclopentadienyl ligands
Van Der Zeijden, Adolphus A. H.,Mattheis, Chris
, p. 847 - 850 (2007/10/03)
Natural (+)-camphene was used as the starting material for the preparation of an isobornyloxy-substituted cyclopentadienyl ligand in a simple two-step procedure. (-)-Menthol and (+)-fenchol were converted to analogous chiral cyclopentadienyl ligands in a four-step procedure. The new ligands contain an ether linkage suitable for bidentate chelation to a transition metal.
