73794-64-6Relevant academic research and scientific papers
SUBSTITUTED AZACYCLOALKANES USEFUL FOR TREATING CNS CONDITIONS
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Page/Page column 39; 56, (2008/06/13)
The invention relates to substituted azacycloalkaπe compounds useful in treating conditions of the Central Nervous System (CNS); a pharmaceutical composition comprising same; a method of treating such conditions and of treating conditions in which inhibition of beta-secretase is indicated.
HETEROCYCLIC CYTOKINE INHIBITORS
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Page/Page column 126, (2010/11/27)
The present invention provides low molecular weight compounds useful as cytokine inhibitors, and compositions thereof. In particular, compounds of the invention are useful as anti-inflammatory, anti-pain or anti-cancer agents. There are further provided m
Reactions of Electron Deficient Dienes with (Acylmethylene)triphenylphosphoranes: One-Pot-Three-Step-Reactions
Flitsch, Wilhelm,Gesing, Ernst Rudolf F.
, p. 3146 - 3153 (2007/10/02)
3a-Azaazulenes (1, 7) react with (acylmethylene)triphenylphosphoranes (2) in a one-pot-three-step-synthesis (Michael addition, intramolecular addition, Wittig elimination) to form cyclohexadiene 1,4-derivatives (3, 8).The course of the reaction is determined by steric requirements which is shown by ethyl 3-isopropylbenzoate (11) formation from ethyl 1,3-cyclohexadiene-1-carboxylate (9) and phosphorane 2b.
