73803-10-8Relevant academic research and scientific papers
Semi-synthetic analogs of pinitol as potential inhibitors of TNF-α cytokine expression in human neutrophils
Bhat, Khurshid A.,Shah, Bhahwal A.,Gupta, Kuldeep K.,Pandey, Anjali,Bani, Sarang,Taneja, Subhash C.
body text, p. 1939 - 1943 (2009/12/03)
Semi-synthetic analogs of pinitol were subjected to screening by determining TNF-α expression in human neutrophils using flowcytometry. Among the tested compounds, three derivatives displayed more than 50% inhibition of TNF-α cytokine secretion in LPS ind
Carbohydrates from Detarium microcarpum bark extract
Abreu, Pedro,Relva, Angela
, p. 1663 - 1666 (2007/10/03)
The bark extract of the medicinal plant Detarium microcarpum was analysed for its carbohydrate content by GLC-CIMS. Preparative HPLC of the benzoylated carbohydrate fraction led to the isolation of L-quino-1,5-lactone, D-(-)-bornesitol, D-pinitol, myo-ino
Mikrobial Oxidation in Synthesis: Preparation of (+)- and (-)-Pinitol from Benzene
Ley, Steven V.,Sternfeld, Francine
, p. 3463 - 3476 (2007/10/02)
Microbial oxidation with Pseudomonas putida of benzene affords cis-1,2-dihydroxycyclohexa-3,5-diene (2) which may be converted in five steps and 49percent overall yield to (+/-)-pinitol.Resolution of an intermediate alcohol (6) with menthoxyacetyl chloride provides optically pure materials which may be independently transformed to (+)- or (-)-pinitol.Demethylation conditions for pinitol together with further reactions of (2) and related compounds were investigated.
