73809-41-3

Basic information

• Product Name: 5,6-cis-1α,25-Dihydroxyvitamin D₃ 3-acetate
• Synonyms: 5,6-cis-1α,25-Dihydroxyvitamin D₃ 3-acetate
• CAS NO: 73809-41-3
• Molecular Weight: 458.682
• Mol File: 73809-41-3.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 5,6-cis-1α,25-Dihydroxyvitamin D₃ 3-acetate(CAS DataBase Reference)
• NIST Chemistry Reference: 5,6-cis-1α,25-Dihydroxyvitamin D₃ 3-acetate(73809-41-3)
• EPA Substance Registry System: 5,6-cis-1α,25-Dihydroxyvitamin D₃ 3-acetate(73809-41-3)

Safety Data

• Hazardous Substances Data: 73809-41-3(Hazardous Substances Data)

Upstream product

• 69822-72-6 25-Hydroxyvitamin D₃ tosylate 
• 64-19-7 acetic acid 
• 67657-80-1 (7E)-(1S,3R,5R,6R)-6-methoxy-3,5-cyclo-9,10-seco-7,10⁽¹⁹⁾-cholestadiene-1,25-diol 
• 98728-23-5 Acetic acid (1S,3R,9S,10R,13R,14R,17R)-1-hydroxy-17-((R)-5-hydroxy-1,5-dimethyl-hexyl)-10,13-dimethyl-2,3,4,9,10,11,12,13,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl ester 
• 61954-91-4 1α,3β,25-trihydroxycholesta-5,7-diene 
• 74080-20-9 (R)-6-{(1R,3aS,7aR)-4-[(R)-2-Methoxy-2-((1R,5R)-2-methylene-bicyclo[3.1.0]hex-1-yl)-eth-(E)-ylidene]-7a-methyl-octahydro-inden-1-yl}-2-methyl-heptan-2-ol 
• 69822-72-6 Toluene-4-sulfonic acid (S)-3-[2-[(1R,3aS,7aR)-1-((R)-5-hydroxy-1,5-dimethyl-hexyl)-7a-methyl-octahydro-inden-(4E)-ylidene]-eth-(Z)-ylidene]-4-methylene-cyclohexyl ester 
• 19356-17-3 calcidiol 
• 74080-20-9 25-Hydroxy-3,5-cyclovitamin D₃ 
• 19356-17-3 25-Hydroxyvitamin D₃ 
• 67657-80-1 1α,25-Dihydroxy-3,5-cyclovitamin D₃ 

Downstream Products

• 98728-28-0 (4-Azido-2-nitro-phenylamino)-acetic acid (1R,3S)-3-hydroxy-5-[2-[(1R,3aS,7aR)-1-((R)-5-hydroxy-1,5-dimethyl-hexyl)-7a-methyl-octahydro-inden-(4E)-ylidene]-eth-(Z)-ylidene]-4-methylene-cyclohexyl ester 
• 98728-26-8 1α-tert-butyldimethylsilylether of 1α-25-dihydroxyvitamin D₃ 
• 157750-00-0 (5Z,7E,1S,3R,10S)-3-acetoxy-9,10-seco-5,7-cholestadiene-1,25-diol 
• 157637-97-3 (5Z,7E,1S,3R,10R)-3-acetoxy-9,10-seco-5,7-cholestadiene-1,25-diol 
• 32222-06-3 1α,25-Dihydroxyvitamin D₃ 

Relevant articles and documents

Synthesis, conformational analysis, and biological-activity of the 1-α,25-dihydroxy-10,19-dihydrovitamin D3 isomers

The synthesis of the four 1α,25-dihydroxy-10,19-dihydrovitamin D3 stereoisomers (8-11) is described starting from 25-hydroxyvitamin D3(1c). Acetic acid-catalyzed cycloreversion of 1 α-hydroxylated 3,5-cyclovitamin D compound 14, prod

Direct C(1) Hydroxylation of Vitamin D3 and Related Compounds

A direct synthesis of C(1) hydroxylated vitamin D analogues from the corresponding vitamin D precursors has been developed.Allylic oxidation of 3,5-cyclovitamin D derivatives, readily obtained from the buffered solvolysis of vitamin D tosylates, with selenium dioxide yields 1α-hydroxylated 3,5-cyclovitamin D compounds which are smoothly converted to the desired 1α-hydroxyvitamin D derivatives by acid-catalyzed cycloreversion.Application of this scheme to vitamin D3 (1a), 25-hydroxyvitamin D3 (1b), and vitamin D2 (1c) affords the 1α-hydroxy products in ca.20 percent overall yield.