73825-95-3Relevant articles and documents
Functionalized tripodal ligands for imaging applications
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, (2008/06/13)
The present invention provides new and structurally diverse compositions for diagnostic imaging comprising compounds of the general formula: STR1 wherein A is N or CR1, R1 is hydrogen, C1 -C8 alkyl, or C6 -C10 aryl, where the alkyl or aryl group may be optionally substituted with one or more hydroxy, C1 -C8 alkyl, C1 -C8 hydroxyalkyl, C1 -C8 alkoxy, C6 -C10 aryl, C6 -C10 hydroxyaryl, C6 -C10 aryloxy, --CO2 R2, --CONR3 R4, or NR3 R4 ; D is O, --O(CH2)2 O--, --O(CH2)3 O--, or NR5 ; E is O, --O(CH2)2 O--, --O(CH2)3 O-- or NR6 ; F is O, --O(CH2)2 O--, --O(CH2)3 O-- or NR7 ; R2 -R7 are as defined within; g, h, i, j, k and m may be the same or different and are an integer from one to about six; X is --CO2 H, --PO3 H2, --SO3 H or --CONHOH.