96-13-9 Usage
Chemical Properties
Different sources of media describe the Chemical Properties of 96-13-9 differently. You can refer to the following data:
1. clear colorless liquid
2. 2,3-Dibromo-1-propanol is a clear, colorless
to slightly yellow thick liquid.
Uses
Different sources of media describe the Uses of 96-13-9 differently. You can refer to the following data:
1. 2,3-Dibromo-1-propanol is a metabolite of the flame retardant tris(2,3-dibromopropyl) phosphate (T775560), previously shown to be a mutagen and carcinogen in experimental animals.
2. The major use of 2,3-dibromo-1-propanol is as an intermediate in the production of flame retardants, insecticides, and pharmaceuticals, and the chemical itself has been used as a flame retardant. 2,3-Dibromo-1-propanol was used in the production of tris(2,3-dibromopropyl) phosphate, a flame retardant used in children’s clothing and other products (HSDB 2009). Tris(2,3-dibromopropyl) phosphate was banned from use in sleepwear in 1977 by the Consumer Product Safety Commission after studies showed that it causedcancer in experimental animals (NTP 1993, HSDB 2009).
3. Synthetic building block, fire-proofing agent, and carcinogen.
Synthesis Reference(s)
The Journal of Organic Chemistry, 30, p. 587, 1965 DOI: 10.1021/jo01013a069
General Description
Clear colorless to slightly yellow viscous liquid.
Air & Water Reactions
Water soluble.
Reactivity Profile
2,3-Dibromo-1-propanol is incompatible with strong oxidizers.
Fire Hazard
2,3-Dibromo-1-propanol is probably combustible.
Potential Exposure
Chemical intermediate used to pro-
duce insecticides, pharmaceuticals, and flame retardants.
Carcinogenicity
2,3-Dibromo-1-propanol is reasonably anticipated to be a human carcinogen based on sufficient evidence of carcinogenicity from studies in experimental animals.
Shipping
UN2810 Toxic liquids, organic, n.o.s., Hazard
Class: 6.1; Labels: 6.1-Poisonous materials, Technical
Name Required.
Check Digit Verification of cas no
The CAS Registry Mumber 96-13-9 includes 5 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 2 digits, 9 and 6 respectively; the second part has 2 digits, 1 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 96-13:
(4*9)+(3*6)+(2*1)+(1*3)=59
59 % 10 = 9
So 96-13-9 is a valid CAS Registry Number.
InChI:InChI=1/C3H6Br2O/c4-1-3(5)2-6/h3,6H,1-2H2/t3-/m0/s1
96-13-9Relevant articles and documents
-
Farkas,Schaechter
, p. 2252 (1949)
-
One-Pot Strategy for Thiazoline Synthesis from Alkenes and Thioamides
Alom, Nur-E,Wu, Fan,Li, Wei
supporting information, p. 930 - 933 (2017/02/26)
A convenient synthesis of a privileged pharmaceutical motif, thiazoline is accomplished. This reaction utilizes simple and readily available alkene and thioamide substrates in an intermolecular fashion via a simple one-pot procedure. A wide range of functional groups is tolerated, and the thiazoline product has been further utilized for the synthesis of the corresponding β-aminothiol and thiazole from routine hydrolysis and oxidation protocols.
Bromination of olefins with HBr and DMSO
Karki, Megha,Magolan, Jakob
, p. 3701 - 3707 (2015/04/22)
A simple and inexpensive methodology is reported for the conversion of alkenes to 1,2-dibromo alkanes via oxidative bromination using HBr paired with dimethyl sulfoxide, which serves as the oxidant as well as cosolvent. The substrate scope includes 21 olefins brominated in good to excellent yields. Three of six styrene derivatives yielded bromohydrins under the reaction conditions.
