7383-30-4

Usage

Uses

Used in Pharmaceutical Industry:
O-a-Dimethyl Tyrosine is used as a pharmaceutical agent for its tyrosine hydroxylase inhibitory properties. As a result, it can be employed in the development of treatments for conditions related to the overproduction or dysregulation of neurotransmitters, such as Parkinson's disease and other neurodegenerative disorders.
Used in Research and Development:
In the field of research and development, O-a-Dimethyl Tyrosine serves as a valuable tool for studying the role of tyrosine hydroxylase in various biological processes. Its inhibitory action allows scientists to investigate the effects of modulating this enzyme on cellular functions and signaling pathways, contributing to a deeper understanding of its implications in health and disease.
Used in Chemical Synthesis:
O-a-Dimethyl Tyrosine can be utilized as a starting material or intermediate in the synthesis of various chemical compounds, particularly those with potential applications in the pharmaceutical, agrochemical, or materials science industries. Its unique structure and reactivity make it a versatile building block for the development of novel molecules with specific properties and functions.

InChI:InChI=1/C11H15NO3/c1-11(12,10(13)14)7-8-3-5-9(15-2)6-4-8/h3-6H,7,12H2,1-2H3,(H,13,14)

Upstream product

• 13500-24-8 5-(4-methoxybenzyl)-5-methylimidazolidine-2,4-dione 
• 1268388-13-1 2-amino-3-(4-methoxyphenyl)-2-methylpropan-1-ol 
• 459-64-3 4-methoxybenzenediazonium tetrafluoroborate 
• 927196-12-1 acetic acid 3-(4-methoxyphenyl)-2-(4-methoxyphenylazo)-2-methylpropyl ester 
• 824-94-2 p-methoxybenzyl chloride 
• 122-84-9 4-methoxybenzyl methyl ketone 
• 70887-29-5 4-methoxybenzyl iodide 

Downstream Products

• 96574-51-5 (S)-N²-acetyl-2,O⁴-dimethyltyrosine 
• 96574-52-6 (R)-N²-acetyl-2,O⁴-dimethyltyrosine 
• 95525-90-9 N²-<(R)-N²-acetyl-2,O⁴-dimethyltyrosyl>-L-phenylalanine dimethylamide 
• 95525-89-6 N²-<(S)-N²-acetyl-2,O⁴-dimethyltyrosyl>-L-phenylalanine dimethylamide 
• 25441-65-0 2-amino-3-(4-methoxyphenyl)-2-methylpropionic acid ethyl ester 
• 7373-63-9 4-Hydroxy-3,5-diiod-α-methyl-phenyl-alanin-aethylester 
• 7434-77-7 2-amino-3-(4-hydroxy-3,5-diiodo-phenyl)-2-methyl-propionic acid 
• 658-48-0 2-amino-3-(4-hydroxy-phenyl)-2-methyl-propionic acid 
• 96574-31-1 N²-acetyl-2,O⁴-dimethyltyrosine 
• 113509-65-2 2-((S)-2-Chloro-propionylamino)-3-(4-methoxy-phenyl)-2-methyl-propionic acid 

Relevant academic research and scientific papers

Chiral azo compounds: Enantioselective synthesis and transformations into β-amino alcohols and α-amino acids with a quaternary stereocenter

Taking advantage of radical carboaminations producing azo compounds, a new chemo-enzymatic approach to enantiomerically enriched azo alcohols, β-amino alcohols and non-natural (aromatic) amino acids with a quaternary stereocenter is reported.

Preparation of α-Branched Phenylalanines and of 1,1-Disubstituted Ethylenediamines via Chiral Imidazolidinones and Oxazolidinones of Glycine - Preparative and Mechanistic Aspects

To test the structural prerequisites for a new carbanionoid rearrangement of 3-methyl-2-pivaloyl-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid to N-(t-butoxycarbonyl)-1-amino-2-methylindan-2-carboxylic acid (A -> B), various α-branched phenylalanines (

SOLID-LIQUID PHASE TRANSFER CATALYTIC SYNTHESIS OF α-AMINO ACID VIA ALKYLATION AND NUCLEOPHILIC ADDITION OF BENZALDEHYDE IMINES

A short, mild and efficient synthetic route of α-amino acid via alkylation, Michael addition and carbonyl addition as well as cycloaddition of aldimines derived from glycine and alanine esters with benzaldehyde under solid-liquid phase transfer catalytic condition has been studied.The key to solid-liquid phase transfer catalyzed reactions is the selection of a base for the various reactants.The yield is dependent on the base used.The results obtained using KOH, K2CO3 and Na2CO3 are discussed.The kinetics of solid-liquid PTC benzylation has been investigated and we propose a possible mechanism of solid-liquid PTC as an interface auto-catalytic procedure.The details of some syntheses of α-amino acids are presented.