73845-01-9Relevant academic research and scientific papers
Synthesis and biological evaluation of substituted phenyl azetidine-2-one sulphonyl derivatives as potential antimicrobial and antiviral agents
Mandal, Milan Kumar,Ghosh, Swagatika,Bhat, Hans Raj,Naesens, Lieve,Singh, Udaya Pratap
, (2020/10/12)
In the present study, we intend to synthesize a series of novel substituted phenyl azetidine-2-one sulphonyl derivatives. The entire set of derivatives 5 (a-t) were screened for in-vitro antibacterial, and antifungal activity, and among them eleven compou
A General Method for Imine Formation Using B(OCH2CF3)3
Reeves, Jonathan T.,Visco, Michael D.,Marsini, Maurice A.,Grinberg, Nelu,Busacca, Carl A.,Mattson, Anita E.,Senanayake, Chris H.
supporting information, p. 2442 - 2445 (2015/05/27)
Tris(2,2,2-trifluoroethyl)borate [B(OCH2CF3)3] was found to be a mild and general reagent for the formation of a variety of imines by condensation of amides or amines with carbonyl compounds. N-Sulfinyl, N-toluenesulfonyl,
γcarbon Activation through N-Heterocyclic Carbene/Bronsted Acids Cooperative Catalysis: A Highly Enantioselective Route to γlactams
Xiao, Yonglong,Wang, Jinxin,Xia, Wenjing,Shu, Shuangjie,Jiao, Shenchao,Zhou, Yu,Liu, Hong
supporting information, p. 3850 - 3853 (2015/08/18)
A carbon activation method that operates through N-heterocyclic carbene/Bronsted acid cooperative catalysis for highly enantioselective synthesis of γlactams is reported. The protocol allows the challenging remote carbon control of regioselectivity and en
Synthesis of cis-C-iodo-N-tosyl-aziridines using diiodomethyllithium: Reaction optimization, product scope and stability, and a protocol for selection of stationary phase for chromatography
Boultwood, Tom,Affron, Dominic P.,Trowbridge, Aaron D.,Bull, James A.
, p. 6632 - 6647 (2013/07/26)
The preparation of C-iodo-N-Ts-aziridines with excellent cis-diastereoselectivity has been achieved in high yields by the addition of diiodomethyllithium to N-tosylimines and N-tosylimine-HSO2Tol adducts. This addition-cyclization protocol succ
Screening of chiral phosphines as catalysts for the enantioselective [3+2] annulations of N-tosylimines with allenic esters
Fleury-Brégeot, Nicolas,Jean, Ludovic,Retailleau, Pascal,Marinetti, Angela
, p. 11920 - 11927 (2008/03/14)
The use of chiral, binaphthyl-based phosphepines as catalysts improves previous results for the enantioselective [3+2] cyclisation reactions between allenic esters and N-tosylimines, both in terms of conversion rate and enantioselectivity. Pyrrolines bear
Highly diastereoselective and enantioselective direct organocatalytic anti-selective Mannich reactions employing N-tosylimines
Cheng, Lili,Han, Xiao,Huang, Huiming,Wong, Ming Wah,Lu, Yixin
, p. 4143 - 4145 (2008/03/18)
Organocatalytic direct anti-selective Mannich reactions of O-TBS-hydroxyacetone with various N-tosylimines derived from aromatic aldehydes in the presence of L-threonine-derived catalyst afforded 1,2-amino alcohols in good yields and with enantioselectivi
