73845-28-0Relevant academic research and scientific papers
CYCLIC DIARYLBORON DERIVATIVES AS NLRP3 INFLAMMASOME INHIBITORS
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Paragraph 00159, (2017/02/24)
Inhibitor compounds are disclosed. The compounds are effective in the treatment of diseases or conditions in which interleukin 1 β activity is implicated. Methods of synthesis of the compounds, as well as pharmaceutical compositions comprising the compounds are also disclosed.
Reactions of β-diketone compounds with nitriles catalyzed by Lewis acids: A simple approach to β-enaminone synthesis
Cheng, Xu,Pei, Shuchen,Xue, Chenchen,Cao, Kaifei,Hai, Li,Wu, Yong
, p. 63897 - 63900 (2015/02/19)
Aluminium chloride selectively promoted the nucleophilic attack of β-diketone compounds with nitriles to give enaminones. Moreover a plausible mechanism for this transformation was given.
Chemistry of hexamethyldisilazane. Silylation of β-diketones and amination of β-triketones
Chu, Daniel T. W.,Huckin, Stuart N.
, p. 138 - 142 (2007/10/02)
It is discovered that hexamethyldisilazane, a reagent generally used to silylate amino, hydroxyl, sulfhydryl, and carbonyl groups, reacts with β-diketones to form their trimethylsilyl enol ethers in high yield.An efficient and simple procedure for aminati
