73853-40-4Relevant academic research and scientific papers
Biomimetic synthesis of 2-substituted N-heterocycle alkaloids by one-pot hydrolysis, transamination and decarboxylative Mannich reaction
Galman, James L.,Slabu, Iustina,Parmeggiani, Fabio,Turner, Nicholas J.
supporting information, p. 11316 - 11319 (2018/10/24)
Heterocycles based on piperidine and pyrrolidine are key moieties in natural products and pharmaceutically active molecules. A novel multi-enzymatic approach based on the combination of a lipase with an α,ω-diamine transaminase is reported, opening up the synthesis, isolation and characterisation of a broad range of 2-substituted N-heterocycle alkaloids.
A BIOGENETICALLY PATTERNED SYNTHESIS OF DEOXYCRYPYOPLEURIDINE
Herbert, Richard B.,Knagg, Eric,Organ, Helen M.,Pasupathy, Vinayager,Towlson, David S.
, p. 409 - 418 (2007/10/02)
The synthesis of two octahydroquinolizines (11) and (13) has been achieved following a biogenetically-patterned route.Oxidative cyclisation of (11) and (13) using thallium(III) trifluoroacetate gave the phenanthroquinolizidines (4) and (6), respectively,
