73861-82-2Relevant academic research and scientific papers
The synthesis of new 1,3-oxazolidines and 1,3-oxazinanes containing (η6-arene)tricarbonylchromium group based on condensation between aldehydes and amino alcohols
Artemov,Sazonova,Krylova,Zvereva,Pechen,Fukin,Cherkasov,Faerman,Grishina, N. Yu.
, p. 884 - 892 (2018/08/28)
The condensation reactions of β- and γ-amino alcohols containing phenyl or (η6-arene) tricarbonylchromium substituent with formaldehyde, acetaldehyde, benzaldehyde, and (η6-benzaldehyde)tricarbonylchromium were studied. The resulting 1,3-oxazolidine and 1,3-oxazinane products were isolated in a pure form and identified by different physicochemical methods. The effect of (η6-arene)tricarbonylchromium moiety on the reaction process was demonstrated.
Unexpected 1,3-oxazolidine formation in the attempted oxidation of N- aryl-N-methyl substituted β-amino alcohols using pyridinium dichromate
Yli-Kauhaluoma, Jari T.,Harwig, Curtis W.,Wentworth Jr., Paul,Janda, Kim D.
, p. 2269 - 2272 (2007/10/03)
1,3-Oxazolidines were obtained from the reaction of N-methyl substituted β-amino alcohols with pyridinium dichromate in dichloromethane. A single electron transfer mechanism, SET, is proposed to account for the formation of the 1,3-oxazolidines.
One-Pot Synthesis of Ethyl 3-(2-Hydroxyalkyl)aminoalkanoates by Ring Opening of 1,3-Oxazolidines Using Reformatsky Reagent
Nishiyama, Tomihiro,Kishi, Hiroshi,Kitano, Kouji,Yamada, Fukiko
, p. 1765 - 1768 (2007/10/02)
Oxazolidines, obtained by the condensation of aldehydes with 2-anilino-1-alkanols, react with the Refortmatsky reagent derived from ethyl bromoacetate under mild reaction conditions to afford ethyl 3-(2-hydroxyalkyl)aminoalkanoates.
