73864-50-3Relevant academic research and scientific papers
Nucleosides and nucleotides, 175. Structural requirements of the sugar moiety for the antitumor activities of new nucleoside antimetabolites, 1-(3- C-ethynyl-β-d-ribo-pentofuranosyl)cytosine and -uracil
Hattori, Hideshi,Nozawa, Eisuke,Iino, Tomoharu,Yoshimura, Yuichi,Shuto, Satoshi,Shimamoto, Yuji,Nomura, Makoto,Fukushima, Masakazu,Tanaka, Motohiro,Sasaki, Takuma,Matsuda, Akira
, p. 2892 - 2902 (2007/10/03)
We previously designed 1-(3-C-ethynyl-β-D-ribo-pentofuranosyl)uracil (EUrd) and its cytosine congener (ECyd) as potential multifunctional antitumor nucleoside antimetabolites. They showed potent and broad-spectrum antitumor activity against various human
BRANCHED-CHAIN SUGAR NUCLEOSIDES. SYNTHESIS OF 3'-C-ETHYL(AND 3'-C-BUTYL)URIDINE
Rosenthal, Alex,Mikhailov, Sergey N.
, p. 235 - 242 (2007/10/02)
Syntheses of 3'-C-ethyl(and 3'-C-butyl)uridine (13 and 15) are described.Addition of ethyl (and butyl)magnesium bromide or the corresponding alkyllithiums to 1,2:5,6-di-O-isopropylidene-α-D-ribo-hexofuranos-3-ulose (1) gave 3-C-ethyl (and 3-C-butyl)-1,2:5
