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Triphenyl(4-pyridinylmethyl)-phosphoniumchloride is a chemical compound with the molecular formula C25H20ClNP. It contains a phosphonium cation and a chloride anion, and is characterized by its white to off-white crystalline powder form. Triphenyl(4-pyridinylmethyl)-phosphoniumchloride is typically handled and stored with care due to its potential toxicity and hazardous properties.

73870-25-4

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73870-25-4 Usage

Uses

Used in Organic Synthesis:
Triphenyl(4-pyridinylmethyl)-phosphoniumchloride is used as a phase transfer catalyst for facilitating the transfer of a reactant from one phase to another, which is crucial in various organic synthesis processes.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, Triphenyl(4-pyridinylmethyl)-phosphoniumchloride is utilized for the preparation of a variety of compounds, contributing to the development of new drugs and medicinal agents.
Used in Agrochemical Industry:
Similarly, in the agrochemical industry, Triphenyl(4-pyridinylmethyl)-phosphoniumchloride is employed in the preparation of different compounds, which can be used in the development of pesticides, herbicides, and other agricultural chemicals to improve crop protection and yield.

Check Digit Verification of cas no

The CAS Registry Mumber 73870-25-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,3,8,7 and 0 respectively; the second part has 2 digits, 2 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 73870-25:
(7*7)+(6*3)+(5*8)+(4*7)+(3*0)+(2*2)+(1*5)=144
144 % 10 = 4
So 73870-25-4 is a valid CAS Registry Number.

73870-25-4SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 13, 2017

Revision Date: Aug 13, 2017

1.Identification

1.1 GHS Product identifier

Product name triphenyl(pyridin-4-ylmethyl)phosphanium,chloride

1.2 Other means of identification

Product number -
Other names 4-pyridinylmethyltriphenylphosphonium chloride

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:73870-25-4 SDS

73870-25-4Downstream Products

73870-25-4Relevant articles and documents

Peptidomimetic Vinyl Heterocyclic Inhibitors of Cruzain Effect Antitrypanosomal Activity

Chenna, Bala C.,Li, Linfeng,Mellott, Drake M.,Zhai, Xiang,Siqueira-Neto, Jair L.,Calvet Alvarez, Claudia,Bernatchez, Jean A.,Desormeaux, Emily,Alvarez Hernandez, Elizabeth,Gomez, Jana,McKerrow, James H.,Cruz-Reyes, Jorge,Meek, Thomas D.

, p. 3298 - 3316 (2020/04/08)

Cruzain, an essential cysteine protease of the parasitic protozoan, Trypanosoma cruzi, is an important drug target for Chagas disease. We describe here a new series of reversible but time-dependent inhibitors of cruzain, composed of a dipeptide scaffold appended to vinyl heterocycles meant to provide replacements for the irreversible reactive "warheads" of vinyl sulfone inactivators of cruzain. Peptidomimetic vinyl heterocyclic inhibitors (PVHIs) containing Cbz-Phe-Phe/homoPhe scaffolds with vinyl-2-pyrimidine, vinyl-2-pyridine, and vinyl-2-(N-methyl)-pyridine groups conferred reversible, time-dependent inhibition of cruzain (Ki? = 0.1-0.4 μM). These cruzain inhibitors exhibited moderate to excellent selectivity versus human cathepsins B, L, and S and showed no apparent toxicity to human cells but were effective in cell cultures of Trypanosoma brucei brucei (EC50 = 1-15 μM) and eliminated T. cruzi in infected murine cardiomyoblasts (EC50 = 5-8 μM). PVHIs represent a new class of cruzain inhibitors that could progress to viable candidate compounds to treat Chagas disease and human sleeping sickness.

Br?nsted acid-catalysed conjugate addition of photochemically generated α-amino radicals to alkenylpyridines

Hepburn, Hamish B.,Melchiorre, Paolo

supporting information, p. 3520 - 3523 (2016/03/04)

The conjugate addition of α-amino radicals to alkenylpyridines has been accomplished by the synergistic merger of Br?nsted acid and visible light photoredox catalysis. Key to reaction development was the protonation of the alkenylpyridines that transientl

MERCAPTOACYL DERIVATIVES OF VARIOUS 4-SUBSTITUTED PROLINES

-

, (2008/06/13)

This invention is directed to compounds of the formula STR1 and various intermediates therefore. The final products possess useful hypotensive activity.

SYNTHESIS OF CAROTENOID ANALOGUES HAVING PYRIDINE, FURAN, AND TIOPHENE RINGS AS TERMINAL GROUPS

Brahmana, Hemat R.,Katsuyama, Kazuki,Inanaga, Junji,Katsuki, Tsutomi,Yamaguchi, Masaru

, p. 1695 - 1696 (2007/10/02)

Heteroaromatic carotenoid analogues having 2-pyridyl, 3-pyridyl, 2-furyl, 3-furyl, 2-thienyl, and 3-thienyl groups at both the ends of tetramethyloctadecanonaene chain, were synthesized and their spectral properties were examined.

Two Step Redox Systems, XXVII. - Vinylogous Bipyridyls and Biquinolyls; Syntheses and UV/VIS-Spectra

Carsky, Petr,Huenig, Siegfried,Stemmler, Ingo,Scheutzow, Dieter

, p. 291 - 304 (2007/10/02)

The vinylogous 2,2'-, 2,4'- and 4,4'-bipyridyls 1(n=2,3), 2(n=2) and 3(n=2,3) together with the corresponding 2,2'-, 2,4'- and 4,4'-biquinolyls 4(n=2,3), 5(n=2) and 6(n=2,3) are synthesized, partly by different routes.Their UV/VIS spectra are described.

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