73881-02-4

Upstream product

• 18476-65-8 1-phenylpenta-4-yn-1-one 
• 108-24-7 acetic anhydride 
• 1254327-43-9 C₁₇H₂₂O 
• 73881-06-8 1-(Bicyclo<2.2.1>hept-5-en-2-yl)-2-(2,4,5-trimethyl-1,3-dioxolan-2-yl)-1-ethanon 
• 52204-67-8 1-(Bicyclo<2.2.1>hept-5-en-2-yl)-1,3-butandion 
• 73880-89-4 1-(2,4,5-Trimethyl-1,3-dioxolan-2-yl)-3-buten-2-on 
• 100-52-7 benzaldehyde 
• 73880-95-2 1-Phenyl-5-(2,4,5-trimethyl-1,3-dioxolan-2-yl)-1,4-pentandion 

Downstream Products

• 1254327-63-3 C₁₃H₁₃BF₂O₃ 

Relevant academic research and scientific papers

Synthesis and characterization of polycarbonyl compounds via their BF 2-adducts

A cobalt-catalyzed 1,4-hydrovinylation reaction is the key step in the synthesis of 1,3-dicarbonyl and higher tri- and tetracarbonyl compounds after ozonolysis of the 1,4-diene intermediates. For the isolation and characterization of the products, the 1,3-dicarbonyl subunits were complexed with a BF2- or a BR2-fragment eliminating the keto-enol tautomerisation. Other 2,3-disubstituted 1,3-butadienes can be generated by a Grubbs enyne metathesis of a symmetrical internal alkyne with ethene. After hydrovinylation and ozonolysis, other 1,3-diketones are accessible.

A FACILE SYNTHESIS OF 1,3-DICARBONYL COMPOUNDS FROM 1-ALKYNE AND ACID ANHYDRIDE PROMOTED BY DICHLORO-BIS(TRIFLUOROMETHANESULFONATO)TITANIUM(IV)

1,3-Dicarbonyl compounds are prepared in high yields by acylation of 1-alkyne derivatives with acid anhydride in the presence of dichloro-bis(trifluoromethanesulfonato)titanium(IV), followed by aqueous work up.

Addition of Aldehydes to Activated Double Bonds, XXIII Syntheses of 1,3,6-Triketones

Thiazolium salt-catalyzed addition of aldehydes to monoacetals of vinyl-1,3-diketones (1, 2; 23, 24) leads to 1,4-diketones (3-10; 25-31), which are hydrolyzed to 1,3,6-triketones (11-18; 32-38).A way to the mono-acetalized vinyl-1,3-diketones 1, 2; 23, 2