7390-76-3

Basic information

• Product Name: (1Z)-5-amino-5-carboxy-1-diazoniopent-1-en-2-olate
• CAS NO: 7390-76-3
• Molecular Formula: C₆H₉N₃O₃
• Molecular Weight: 171.154
• Mol File: 7390-76-3.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: (1Z)-5-amino-5-carboxy-1-diazoniopent-1-en-2-olate(CAS DataBase Reference)
• NIST Chemistry Reference: (1Z)-5-amino-5-carboxy-1-diazoniopent-1-en-2-olate(7390-76-3)
• EPA Substance Registry System: (1Z)-5-amino-5-carboxy-1-diazoniopent-1-en-2-olate(7390-76-3)

Safety Data

• Hazardous Substances Data: 7390-76-3(Hazardous Substances Data)

Upstream product

• 25830-77-7 N-phthaloyl-L-glutamic anhydride 
• 150823-38-4 N-phthaloyl glutamic acid α-methyl ester 
• 71989-18-9 Fmoc-Glu(OtBu)-OH 
• 208520-02-9 ethyl 2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-6-diazo-5-oxohexanoate 
• 42294-25-7 (2S)-2-(1,3-dioxo-1,3-dihydroisoindol-2-yl)pentanedioic acid α-methyl ester 
• 25830-78-8 N-phthaloyl-D-glutamic acid anhydride 
• 42294-25-7 N,N-phthaloyl-D-glutamic acid-1-methyl ester 
• 56-86-0 L-glutamic acid 
• 160002-61-9 N-(9-fluorenylmethoxycarbonyl)glutamic acid (O-tert-butyl) methyl ester 
• 7589-24-4 6-Diazo-5-oxo-N-Tfa-L-norleucine-OMe 
• 884594-54-1 (S)-6-diazo-5-oxo-2-(2,2,2-trifluoro-acetylamino)-hexanoic acid ethyl ester 
• 6893-26-1 D-Glutamic acid 
• 367-95-3 (S)-4-Chlorcarbonyl-2-(trifluor-acetylamino)butansaeureethylester 
• 84344-29-6 N-Tfa-L-Glu-OMe-γ-Dcha Salt 

Downstream Products

• 146467-21-2 (S)-5-oxo-2-piperidinecarboxylic acid 
• 82972-54-1 4-amino-4-deoxy-N¹⁰-methylpteroyl-(6-diazo-5-oxo)-L-norleucine 

Relevant articles and documents

Chemical reactivity of 6-diazo-5-oxo-l-norleucine (DON) catalyzed by metalloporphyrins (Fe,Ru)

The transfer of the metallocarbene derived from N- and O-protected 6-diazo-5-oxo-l-norleucine (DON) catalyzed by metalloporphyrins undergoes dimerization, cyclopropanation, N-H and S-H insertion reactions, respectively. An efficient and direct synthesis of 5-oxo-l-pipecolic acid from DON is described from unprotected 6-diazo-5-oxo-l-norleucine.

The Reaction of Lithium Trimethylsilyldiazomethane with Pyroglutamates - a Facile Synthesis of 6-Diazo-5-oxo-norleucine and Derivatives

The reaction of carbamate derivatives of pyroglutamic acid esters with the lithium salt of trimethylsilyldiazomethane below -100 deg C gives good yields of the corresponding substituted 6-diazo-5-oxo-norleucine esters; cleavage of Fmoc-substituted products provides a safe, convenient route to the parent acid.