73926-98-4

Basic information

• Product Name: 1-(4-methoxyphenyl)-3-methylidenepyrrolidine-2,5-dione
• Synonyms: 2,5-Pyrrolidinedione, 1- (4-methoxyphenyl)-3-methylene-; 2,5-pyrrolidinedione, 1-(4-methoxyphenyl)-3-methylene-
• CAS NO: 73926-98-4
• Molecular Formula: C₁₂H₁₁NO₃
• Molecular Weight: 217.2206
• Mol File: 73926-98-4.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 366°C at 760 mmHg
• Flash Point: 175.1°C
• Density: 1.26g/cm³
• Vapor Pressure: 1.51E-05mmHg at 25°C
• Refractive Index: 1.589
• CAS DataBase Reference: 1-(4-methoxyphenyl)-3-methylidenepyrrolidine-2,5-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(4-methoxyphenyl)-3-methylidenepyrrolidine-2,5-dione(73926-98-4)
• EPA Substance Registry System: 1-(4-methoxyphenyl)-3-methylidenepyrrolidine-2,5-dione(73926-98-4)

Safety Data

• Hazardous Substances Data: 73926-98-4(Hazardous Substances Data)

Usage

General Description

1-(4-methoxyphenyl)-3-methylidenepyrrolidine-2,5-dione is a chemical compound with the molecular formula C14H13NO3. It is a pyrrolidine derivative that possesses a phenyl group attached to the nitrogen atom and a methoxy group attached to the benzene ring. The chemical structure also contains a methylidene group attached to the pyrrolidine ring, as well as a dione functional group. 1-(4-methoxyphenyl)-3-methylidenepyrrolidine-2,5-dione has potential applications in medicinal chemistry due to its structural features, which may allow it to interact with biological targets in the body. Further research and investigation into the properties and potential uses of 1-(4-methoxyphenyl)-3-methylidenepyrrolidine-2,5-dione are necessary to fully understand its potential.

Upstream product

• 2170-03-8 itaconic acid anhydride 
• 104-94-9 4-methoxy-aniline 
• 74448-29-6 N-<4-Methoxy-phenyl>-2-methylen-succinamidsaeure 

Downstream Products

• 1392115-13-7 (S)-(+)-methyl 2-((1-(4-methoxyphenyl)-4-methyl-2,5-dioxo-2,5-dihydro-1H-pyrrol-3-yl)(phenyl)methyl)acrylate 
• 1234887-96-7 3-(tert-butylthiomethyl)-1-(4-methoxyphenyl)pyrrolidine-2,5-dione 

Relevant articles and documents

N-Aryl-3-mercaptosuccinimides as Antivirulence Agents Targeting Pseudomonas aeruginosa Elastase and Clostridium Collagenases

In light of the global antimicrobial-resistance crisis, there is an urgent need for novel bacterial targets and antibiotics with novel modes of action. It has been shown that Pseudomonas aeruginosa elastase (LasB) and Clostridium histolyticum (Hathewaya histolytica) collagenase (ColH) play a significant role in the infection process and thereby represent promising antivirulence targets. Here, we report novel N-Aryl-3-mercaptosuccinimide inhibitors that target both LasB and ColH, displaying potent activities in vitro and high selectivity for the bacterial over human metalloproteases. Additionally, the inhibitors demonstrate no signs of cytotoxicity against selected human cell lines and in a zebrafish embryo toxicity model. Furthermore, the most active ColH inhibitor shows a significant reduction of collagen degradation in an ex vivo pig-skin model.

Synthesis of cyclic imides (methylphtalimides, carboxylic acid phtalimides and itaconimides) and evaluation of their antifungal potential

Background: This paper describes the synthesis of three different subfamilies of cyclic imides: methylphtalimides, carboxyl acid phtalimides and itaconimides. Methods: Fifteen compounds (five of each sub-family) were obtained by the reaction of appropriat