74003-55-7

Basic information

• Product Name: 3,4-Dibromobenzaldehyde
• Synonyms: 3,4-DIBROMOBENZALDEHYDE;3,4-Dibromobenzaldehyde 99%;1,2-Dibromo-4-formylbenzene;3,4-Dibromobenzaldehyde99%
• CAS NO: 74003-55-7
• Molecular Formula: C₇H₄Br₂O
• Molecular Weight: 263.91
• EINECS: -0
• Product Categories: Adehydes, Acetals & Ketones;Bromine Compounds
• Mol File: 74003-55-7.mol
• Article Data: 2

Chemical Properties

• Melting Point: 67-69°C
• Boiling Point: 303.6°C at 760 mmHg
• Flash Point: 123°C
• Appearance: /
• Density: 1.977g/cm³
• Vapor Pressure: 0.00092mmHg at 25°C
• Refractive Index: 1.645
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• Water Solubility: Insoluble in water.
• Sensitive: Air Sensitive
• BRN: 2573433
• CAS DataBase Reference: 3,4-Dibromobenzaldehyde(CAS DataBase Reference)
• NIST Chemistry Reference: 3,4-Dibromobenzaldehyde(74003-55-7)
• EPA Substance Registry System: 3,4-Dibromobenzaldehyde(74003-55-7)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36
• Hazardous Substances Data: 74003-55-7(Hazardous Substances Data)

Usage

Uses

3,4-Dibromobenzaldehyde is used in the preparation of isomeric branched pi-conjugated system with terminal alkyne by reacting with 4-(triisopropylsilylethynyl) phenylacetylene.

InChI:InChI=1/C7H4Br2O/c8-6-2-1-5(4-10)3-7(6)9/h1-4H

Upstream product

• 68119-98-2 1,2-dibromo-4-(hydroxymethyl)benzene 
• 1122-91-4 4-bromo-benzaldehyde 
• 163596-75-6 4-bromo-3-nitrobenzaldehyde 

Downstream Products

• 1440251-86-4 2-(benzo[d][1,3]dioxol-5-yl)-N-(3,4-dibromobenzyl)pyrimidin-4-amine 
• 1440251-05-7 4-(benzo[d][1,3]dioxol-5-yl)-N-(3,4-dibromobenzyl)pyrimidin-2-amine 
• 390407-76-8 2-(3,4-dibromo-phenyl)-oxirane 
• 619-03-4 3,4-dibromobenzoic acid 

Relevant articles and documents

Co-immobilization of Laccase and TEMPO in the Compartments of Mesoporous Silica for a Green and One-Pot Cascade Synthesis of Coumarins by Knoevenagel Condensation

Co-immobilization of bio- and chemocatalysts produces sustainable, recyclable hybrid systems that open new horizons for green cascade approaches in organic synthesis. Here, the co-immobilization of laccase and 2,2,6,6-tetramethylpiperidin-1-oxyl (TEMPO) in mesoporous silica was used for the one-pot aqueous synthesis of 30 coumarin-3-carboxylate derivatives under mild conditions through the condensation of in situ oxidized 2-hydroxybenzyl alcohols and malonate derivatives. A maximum yield was obtained after incubating at pH 6.0 and 45 °C for 24 h. An efficient organic synthesis was catalyzed by the hybrid catalyst in 10 % organic solvent. More than 95 % of the initial activity of the enzyme was preserved after 10 cycles, and no significant catalyst deactivation occurred after 10 runs. This new system efficiently catalyzed the in situ aerobic oxidation of salicyl alcohols, followed by Knoevenagel condensation, which confirmed the possibility of producing efficient hybrid catalysts by co-immobilization of catalytic species in mesoporous materials.