7401-89-0

Usage

Uses

Used in Chemical Industry:
2,4,5,6-tetrachlorobenzene-1,3-dicarboxylic acid is used as a chemical intermediate for the production of dyes and pigments, contributing to the coloration and stability of various products.
Used in Environmental Management:
Due to its potential toxic and environmental effects, 2,4,5,6-tetrachlorobenzene-1,3-dicarboxylic acid is used in the development of strategies for proper handling, disposal, and management to minimize its persistence in the environment and bioaccumulation in organisms.
Used in Health and Safety Regulations:
2,4,5,6-tetrachlorobenzene-1,3-dicarboxylic acid is considered in the establishment of health and safety regulations to ensure that humans and other organisms are protected from potential risks associated with its use and disposal.

Upstream product

• 130199-76-7 perchloro-m-xylene 
• 121-91-5 isophthalic acid 
• 7664-93-9 sulfuric acid 
• 880-76-2 2,3,4,6-tetrachloro-5-methyl-benzoic acid 
• 124-38-9 carbon dioxide 
• 118-74-1 hexachlorobenzene 
• 108-70-3 1,3,5-trichlorobenzene 
• 130199-73-4 2,4,6-trichloro-1,3-bis(trifluoromethyl)benzene 
• 130199-75-6 2,4,6-trichloro-1,3-bis(trichloromethyl)benzene 

Downstream Products

• 1622987-90-9 C₈Cl₄O₄^(2-)*Cu⁽²⁺⁾*C₃H₇NO*H₂O 

Relevant academic research and scientific papers

Electrocarboxylation of chlorinated aromatic compounds

Chorinated benzenes (1, 4), biphenyls (6, 9), dibenzofurans (10, 15, 17, 18), 2-chlorodibenzo[1,4]dioxine (24) and 1-chloronaphthalene (26) as well as dibenzofuran (12) and naphthalene (27) themselves were transformed into carboxylic acids by galvanostatic electroreduction in the presence of carbon dioxide ("electrocarboxylation"). Dry DMF was used as solvent, zinc or stainless steel as cathode and magnesium as a sacrificial anode in an undivided cell. Hydrogenation of aromatic rings was not observed. However, reductive addition of two molecules of carbon dioxide to form dihydrodicarboxylic acids, e.g. 22 and 29, occurs in the dibenzofuran and naphthalene series.

A New Trifluoromethylating Agent: Synthesis of Polychlorinated (Trifluoromethyl)benzenes and 1,3-Bis(trifluoromethyl)benzenes and Conversion into Their Trichloromethyl Counterparts and Molecular Structure of Highly Strained Polychloro-m-xylenes

Mixtures of CCl3F and AlCl3 replace CF3 for H in polychlorobenzenes.Thus, by treatment of a solution of the suitable polychlorobenzene in CCl3F with AlCl3, the following compounds can be prepared: pentachloro- (2), 2,3,4,5-tetrachloro- (5), 2,3,4,6-tetrachloro- (8), 2,3,5,6-tetrachloro- (11), 2,3,4-trichloro- (14), 2,4,5-trichloro- (17), and 2,4,6-trichloro-1-(trifluoromethyl)benzene (20), as well as 4,5,6-trichloro- (31) and 2,4,6-trichloro-1,3-bis(trifluoromethyl)benzene (32).The reaction of the above-mentioned trifluoromethylated compounds with AlCl3 in CS2 yieldstheir trichloromethyl counterparts: 3, 6, 9, 12, 15, 18, 21, 34, and 36.The chlorination of 32 or 36 by means of Silberrad's reagent (SO2Cl2, AlCl3, and S2Cl2) affords perchloro-m-xylene (38), a new highly strained chlorocarbon whose synthesis was attempted repeatedly in the past. 9, 15, 17, and 21, when treated with oleum and then with water, are converted into 2,3,4,6-tetrachloro- (22), 2,3,4-trichloro- (23), 2,4,5-trichloro- (24), and 2,4,6-trichlorobenzoic acid (25), respectively; under similar treatment, 34, 36, and 38 give 4,5,6-trichloro- (33), 2,4,5-trichloro- (35), and tetrachloroisophthalic acid (39), respectively.The formation of the (trifluoromethyl)benzenes is discussed, and in this connection it has been found that CCl3F solutions of 3 and 18 in the presence of AlCl3 give back 2 and 17, respectively.Molecular structures of highly strained m-xylenes 36 and 38, as well as that of the much less strained 34, ascertained by X-ray analysis, are reported and commented.IR, UV, and NMR spectral data of the compounds synthesized are presented.The interesting UV spectrum of 21 is discussed.