7402-54-2

Usage

Uses

Used in Organic Synthesis:
N-(4-methoxy-2-methyl-phenyl)formamide is used as an intermediate in organic synthesis for the production of various drugs and pharmaceuticals.
Used in Pharmaceutical Research:
In pharmaceutical research, N-(4-methoxy-2-methyl-phenyl)formamide is used as a building block for the synthesis of novel pharmaceutical compounds.
Used in Medicinal Chemistry:
N-(4-methoxy-2-methyl-phenyl)formamide is important in medicinal chemistry due to its potential biological and pharmacological properties, such as antibacterial and anti-inflammatory effects.

InChI:InChI=1/C9H11NO2/c1-7-5-8(12-2)3-4-9(7)10-6-11/h3-6H,1-2H3,(H,10,11)

Upstream product

• 64-18-6 formic acid 
• 102-50-1 2-methyl-4-methoxyaniline 

Downstream Products

• 1930-89-8 1-isocyano-4-methoxy-2-methylbenzene 

Relevant academic research and scientific papers

PYRIMIDINE COMPOUNDS AND PYRIMIDO INDOLE COMPOUNDS AND METHODS OF USE

The present invention discloses substituted pyrimidine and pyrimido indole compounds and optionally pharmaceutically acceptable salts, hydrates or solvates thereof. A method of treating a patient having cancer or a disease comprising administering to a patient an effective amount of the compound or pharmaceutically acceptable salt, hydrate, or solvate thereof.

Screw Sense Selective Polymerization of Achiral Isocyanides Catalysed by Optically Active Nickel(II) Complexes

Poly(isocyanides), (RN=Cn, can be prepared from isocyanides, , by the catalytic action of nickel(II) compounds.The main chain of these polymers is a rigid helix.This helical conformation results from a restricted rotation around the single bonds that connect the main-chain carbon atoms.Polymerization of achiral isocyanides generally gives a racemic mixture of left- and right-handed helices, whereas polymerization of optically active isocyanides results in helices with an excess of one screw sense.We describe a procedure for obtaining poly(isocyanides) with predominantly one screw sense, starting from an achiral monomer.A catalyst is prepared by adding an optically active amine to a tetrakis(isocyanide)nickel(II) perchlorate complex.Polymerization of various achiral isocyanides with this catalist yields optically active polymers with an enantiomeric excess up to 83percent.