7404-77-5 Usage
Uses
Used in Perfumery and Cosmetics:
1-(2-hydroxy-2,5-dimethyl-5-nitrocyclohexyl)ethanone is used as a fragrance compound in the perfumery and cosmetic industries for its distinctive musky odor. The synthetic nature of muscone allows for a more ethical and sustainable alternative to natural musk, which has been a point of concern due to the methods of extraction from musk deer.
Used as a Flavoring Agent:
In the food and beverage industry, 1-(2-hydroxy-2,5-dimethyl-5-nitrocyclohexyl)ethanone is used as a flavoring agent to impart a unique taste and aroma to various products. Its powerful musky scent adds depth and complexity to the flavor profiles of different culinary creations.
Used in Chemical Production:
1-(2-hydroxy-2,5-dimethyl-5-nitrocyclohexyl)ethanone also serves as a key intermediate in the synthesis of other chemicals, contributing to its versatility and importance in the chemical industry. Its role in chemical production highlights the compound's utility beyond the realms of fragrance and flavoring.
Check Digit Verification of cas no
The CAS Registry Mumber 7404-77-5 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 7,4,0 and 4 respectively; the second part has 2 digits, 7 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 7404-77:
(6*7)+(5*4)+(4*0)+(3*4)+(2*7)+(1*7)=95
95 % 10 = 5
So 7404-77-5 is a valid CAS Registry Number.
7404-77-5Relevant academic research and scientific papers
Michael reaction of stabilized carbon nucleophiles catalyzed by [RuH2(PPh3)4]
Gómez-Bengoa, Enrique,Cuerva, Juan M.,Mateo, Cristina,Echavarren, Antonio M.
, p. 8553 - 8565 (2007/10/03)
The Michael reaction of active methylene compounds lacking cyano groups such as malonates, β-ketoesters, 1,3-diketones, 1,1-disulfones, nitrocompounds, Meldrum acid, and anthrone with common acceptors proceeds in acetonitrile solution in the presence of [RuH2(PPh3)4] as the catalyst. Cyano acetates, more acidic than malonates in organic solvents, are also excellent substrates for this reaction. In a number of cases, intramolecular aldol reactions catalyzed by [RuH2(PPh3)4] were also observed as side reactions. Catalysis by other ruthenium and rhodium complexes has been examined. Selectivity studies performed with malonate and disulfone donors indicate that the catalyst selectively activates Michael donors that can coordinate with ruthenium(II). Additionally, it has been shown that the reaction requires the presence of free phosphine. Therefore, the Michael reaction of stabilized enolates appears to be a ruthenium- and phosphine-catalyzed reaction. From a practical point of view, the use of readily prepared [RuH2(PPh3)4] as the catalyst in acetonitrile provided the best solution for the Michael reaction of active methylene compounds.
