74073-23-7Relevant articles and documents
2,6-Dimethyl-4-2,3-disubstituted phenyl-1,4-dihydro-pyridine-3,5-dicarboxylic acid-3,5-asymmetric diesters having hypotensive properties, as well as method for treating hypertensive conditions and pharmaceutical preparations containing same
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, (2008/06/13)
The present invention relates to new compounds having antihypertensive effect, which compounds are of the formula I, STR1 wherein R1 is selected from the group consisting of --CH3, --C2 H5, --CH2 CH2 OCH3, and --CH2 CH2 OC2 H5, and R2 is selected from the group consisting of --C2 H5, --CH(CH3)2, --C(CH3)3, --CH(CH3)CH2 OCH3, C(CH3)2 CH2 OCH3, and --CH2 C(CH3)=CH2, whereby R1 and R2 are not the same, R3 is selected from the group consisting of chloro, and R4 is selected from the group consisting of chloro, and methyl, a method for lowering the blood pressure in mammals including man using said compounds, and pharmaceutical preparations containing said compounds.