74074-09-2

Basic information

• Product Name: 4H-1-Benzothiopyran-4-one, 2,3-dihydro-3-(phenylmethylene)-
• Synonyms: Z-3-benzylidene-1-thiochromanone;3-Benzyliden-thiochroman-4-on;3-benzylidene-3,4-dihydro-2H-1-benzothiin-4-one;3-benzylidene-thiochroman-4-one
• CAS NO: 74074-09-2
• Molecular Formula: C16H12OS
• Molecular Weight: 252.337
• Mol File: 74074-09-2.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: 4H-1-Benzothiopyran-4-one, 2,3-dihydro-3-(phenylmethylene)-(CAS DataBase Reference)
• NIST Chemistry Reference: 4H-1-Benzothiopyran-4-one, 2,3-dihydro-3-(phenylmethylene)-(74074-09-2)
• EPA Substance Registry System: 4H-1-Benzothiopyran-4-one, 2,3-dihydro-3-(phenylmethylene)-(74074-09-2)

Safety Data

• Hazardous Substances Data: 74074-09-2(Hazardous Substances Data)

Upstream product

• 3528-17-4 2,3-dihydro-4H-[1]benzothiopyran-4-one 
• 100-52-7 benzaldehyde 
• 78140-85-9 3-hydroxybenzylthiochroman-4-one 

Downstream Products

• 109754-26-9 C₁₇H₁₄N₂OS 
• 93362-79-9 7,7a,8,9,10,11-Hexahydro-7-phenyl-11a-piperidino-6H,11aH<1>benzothiopyrano<4,3-b>chromen 
• 116924-21-1 4-phenyl-(5H)-(1-benzthiopyrano)-(4,3-d)-1,2,3,4-tetrahydropyrimidine-2-thione 
• 137985-57-0 1-Phenyl-1H,10H-2,9-dithia-4-aza-phenanthren-3-ylamine 
• 87604-66-8 (6aR,7S)-7-Phenyl-6a,7-dihydro-6H-5,8-dithia-13-aza-benzo[5,6]cyclohepta[1,2-a]naphthalene 
• 78140-88-2 3-benzylthiochroman-4-one 
• 76238-58-9 3-benzylidene-1-thiochromanol 
• 121802-92-4 3-Phenyl-3a,4-dihydro-3H-thiochromeno[4,3-c]pyrazole-2-carbothioic acid amide 
• 142929-05-3 6,6a,7,8-Tetrahydro-7-phenylbenzo<1>benzothiopyrano<4,3-e><1,4>diazepine 
• 346467-42-3 3-benzyl-4H-thiochromen-4-one 
• 1373520-31-0 (2R,3S,3aR)-tert-butyl 3-phenyl-2,3,3a,4-tetrahydrothiochromeno[4,3-b]pyrrole-2-carboxylate 
• 1262801-78-4 (R)-2-amino-4-phenyl-4,5-dihydrothiochromeno[4,3-b]pyran-3-carbonitrile 
• 1262616-81-8 (2'S,3S,4'R)-4'-hydroxy-2'-phenyl-3,3'-spirobi[thiochroman]-4-one 
• 78140-87-1 cis-3-benzylthiochroman-4-ol-acetate 

Relevant articles and documents

I2/TBHP mediated diastereoselective synthesis of spiroaziridines

Eventhough spiroheterocycles are considered as emerging drug candidates, synthesis of spiroaziridines has not been well explored so far. Herein, we disclose an efficient I2/TBHP mediated diastereoselective synthesis of N-alkyl spiroaziridines from primary amines and easily accessible α,β-unsaturated ketones. The reaction is also compatible for the synthesis of 2-aroylaziridines.

Reactivity of α-arylidene benzoheteracyclanone dibromides toward azide ion: An effective approach to 3-(α-substituted-benzyl)chromones and -1-thiochromones

Treatment of dibromides of 3-arylidenechromanones and -1-thiochromanones with sodium azide resulted in the formation of 3-(α-azidobenzyl)chromones and -1-thiochromones whereas dibromides having no antiperiplanar vicinal hydrogen in the ring such as flavanone, 1-thioflavanone and benzosuberone derivatives afforded only the parent enones by bromine elimination. Evidence supported the intermediacy of 3-(α-bromobenzyl)chromones and -1-thiochromones in this reaction. These postulated intermediates were prepared in an independent way and transformed into azides in high yield.

CYCLIC UNSATURATED KETONES. VI. 3-ARYLIDENE-1-THIO-4-CHROMANONES

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