74077-08-0

Basic information

• Product Name: 2-Phenyl-1,1-bis(trifluoracetoxy)ethan
• CAS NO: 74077-08-0
• Molecular Weight: 330.184
• Mol File: 74077-08-0.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 2-Phenyl-1,1-bis(trifluoracetoxy)ethan(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Phenyl-1,1-bis(trifluoracetoxy)ethan(74077-08-0)
• EPA Substance Registry System: 2-Phenyl-1,1-bis(trifluoracetoxy)ethan(74077-08-0)

Safety Data

• Hazardous Substances Data: 74077-08-0(Hazardous Substances Data)

Upstream product

• 100-42-5 styrene 
• 2712-78-9 bis-[(trifluoroacetoxy)iodo]benzene 
• 407-25-0 trifluoroacetic anhydride 
• 14353-86-7 iodine tris(trifluoroacetate) 

Relevant articles and documents

On the regioselectivity of the PIFA-mediated bis(trifluoroacetoxylation) of styrene-type compounds

The addition of the hypervalent iodine reagent PIFA [phenyliodine(III) bis(trifluoroacetate)] to a series of styrene-type compounds results in the bis(trifluoroacetoxylation) of the double bond as two possible 1,2- and 1,1-regioisomers. We found that 1,1-regioisomers resulted to be unstable during chromatographic purification yielding the related arylacetaldehydes. In this paper, we show our efforts to explore the regioselectivity of this reaction, and to rationalize the results with respect to the electronic nature of the corresponding aryl ring through alternative mechanistic pathways.