740798-72-5

Upstream product

• 24424-99-5 di-tert-butyl dicarbonate 
• 5194-51-4 (2E)-2,6-hexadiene 
• 740798-68-9 acetic acid 2,2-dimethyl-5-nitroso-[1,3]dioxan-5-yl ester 
• 36016-38-3 tert-Butyl N-hydroxycarbamate 

Relevant academic research and scientific papers

Synthesis of polysubstituted pyrroles from nitroso-diels-alder cycloadducts

Nitroso-Diels-Alder cycloaddition of various dienes combined with a straightforward sequence including N-O bond cleavage and oxidation reaction of the resulting (Z)-γ-aminoenone (or enal) leads to polysubstituted pyrrolic units. Georg Thieme Verlag Stuttg

Lewis acid-promoted hetero Diels-Alder cycloaddition of α-acetoxynitroso dienophiles

(Equation Presented) α-Acetoxynitroso compound 3 has been prepared as a new stable, isolable, and reactive dienophile in nitroso Diels-Alder reactions. The yield of the [4 + 2] cycloaddition of α-acetoxynitroso dienophile with 1,3-dienes could be enhanced in the presence of 20 mol % Lewis acid. An unexpected retro hetero-Michael reaction from 26 was observed, leading to the cleavage of the N-O bond of the cycloadduct. This tandem nitroso Diels-Alder/retro hetero-Michael sequence has been used with cyclic and acyclic 1,3-dienes.