740802-83-9

Upstream product

• 132127-27-6 (1R,2S)-2-phenyl-1-cyclohexyl<(triisopropylsilyl)oxy>acetate 
• 140236-11-9 N-(4-methoxyphenyl)-3-methyl-2-butenaldimine 
• 13154-24-0 triisopropylsilyl chloride 
• 740802-58-8 (3S,4R)-1-(4-methoxyphenyl)-3-hydroxy-4-(2-methyl-1-propenyl)azetidin-2-one 
• 104-94-9 4-methoxy-aniline 
• 107-86-8 3,3-dimethyl acrylaldehyde 

Downstream Products

• 740802-79-3 (3S,4S)-1-benzyloxycarbonyl-3-triisopropylsiloxy-4-difluoromethylazetidin-2-one 
• 740802-80-6 (3S,4S)-1-(4-methylbenzenesulfonyl)-3-triisopropylsiloxy-4-difluoromethylazetidin-2-one 
• 740802-81-7 (3S,4S)-1-(4-fluorobenzoyl)-3-triisopropylsiloxy-4-difluoromethylazetidin-2-one 
• 740802-85-1 (3S,4S)-4-Difluoromethyl-1-(4-methoxy-phenyl)-3-triisopropylsilanyloxy-azetidin-2-one 
• 740802-84-0 (3S,4R)-1-p-methoxyphenyl-3-triisopropylsiloxy-4-formylazetidin-2-one 

Relevant academic research and scientific papers

Trifluoromethyl- and difluoromethyl-β-lactams as useful building blocks for the synthesis of fluorinated amino acids, dipeptides, and fluoro-taxoids

Enantiopure 1-acyl-3-hydroxyl-4-CF2H-azetidin-2-ones and 1-acyl-3-hydroxy-4-CF3-azetidin-2-ones serve as versatile intermediates for the syntheses of CF2- and CF3-containing α-hydroxy-β-amino acids, dipeptides,

Syntheses and structure-activity relationships of taxoids derived from 14β-hydroxy-10-deacetylbaccatin III

A series of new taxoids derived from 14β-hydroxy-10-deacetylbaccatin III was synthesized by means of the β-lactam synthon method. Most of the new taxoids thus synthesized possess excellent cytotoxicity against human ovarian (A121), non-small-cell lung (A5