740832-42-2

Basic information

• Product Name: 1-(2,4-difluorophenyl)-2-(5-{2-[4-(2-methoxyphenyl)piperazin-1-yl]ethyl}tetrazol-1-yl)propan-1-one
• Synonyms: 1-(2,4-difluorophenyl)-2-(5-{2-[4-(2-methoxyphenyl)piperazin-1-yl]ethyl}tetrazol-1-yl)propan-1-one
• CAS NO: 740832-42-2
• Molecular Weight: 456.495
• Mol File: 740832-42-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1-(2,4-difluorophenyl)-2-(5-{2-[4-(2-methoxyphenyl)piperazin-1-yl]ethyl}tetrazol-1-yl)propan-1-one(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(2,4-difluorophenyl)-2-(5-{2-[4-(2-methoxyphenyl)piperazin-1-yl]ethyl}tetrazol-1-yl)propan-1-one(740832-42-2)
• EPA Substance Registry System: 1-(2,4-difluorophenyl)-2-(5-{2-[4-(2-methoxyphenyl)piperazin-1-yl]ethyl}tetrazol-1-yl)propan-1-one(740832-42-2)

Safety Data

• Hazardous Substances Data: 740832-42-2(Hazardous Substances Data)

Upstream product

• 126917-43-9 2-chloro-1-(2,4-difluorophenyl)propan-1-one 
• 740831-34-9 1-(2-methoxyphenyl)-4-[2-(1H-tetrazol-5-yl)-ethyl]-piperazine 

Downstream Products

• 1025824-21-8 1-[2-(1-{1-[2-(2,4-difluoro-phenyl)-oxiranyl]-ethyl}-1H-tetrazol-5-yl)-ethyl]-4-(2-methoxy-phenyl)-piperazine 

Relevant articles and documents

Synthesis of novel substituted tetrazoles having antifungal activity

In an effort to find potent antifungal agents, a variety of triazole derivatives with a 5-substituted tetrazole structure 6, 7, 12 and 14 were prepared and evaluated for antifungal activity against Candida spp., Cryptococcus neoformans, and Aspergillus spp. in vitro. The location of the methyl group at the C-3 of compounds 12 and 14 has been demonstrated to be a key structural element of antifungal potency.