740835-26-1Relevant articles and documents
Rapid purification of small molecule libraries by ion exchange chromatography
Siegel, Miles G.,Hahn, Patric J.,Dressman, Bruce A.,Fritz, James E.,Grunwell, Jocelyn R.,Kaldor, Stephen W.
, p. 3357 - 3360 (1997)
Amines and acylated amines are synthesized in traditional solution phase reactions, then rapidly purified by ion exchange chromatography to yield pure products. In some instances, impurities devoid of ionizable functionality can be covalently modified pri