74130-05-5

Usage

Uses

Used in Pharmaceutical Industry:
4-(4-BROMO-PHENOXY)-PIPERIDINE is used as an intermediate in the synthesis of pharmaceuticals for its ability to contribute to the development of new drugs with potential therapeutic effects.
Used in Agrochemical Industry:
4-(4-BROMO-PHENOXY)-PIPERIDINE is also utilized as an intermediate in the synthesis of agrochemicals, playing a role in the creation of substances that can enhance crop protection and productivity.
Used in Serotonin 5-HT3 Receptor Antagonism:
4-(4-BROMO-PHENOXY)-PIPERIDINE is used as a serotonin 5-HT3 receptor antagonist, indicating its potential role in treating conditions related to serotonin dysregulation, such as nausea, vomiting, and certain psychiatric disorders.
Used in Organic Compound Preparation:
It serves as a building block in the preparation of various organic compounds, highlighting its importance in organic chemistry and the synthesis of complex molecules with specific properties and applications.

Upstream product

• 106-41-2 4-bromo-phenol 
• 109384-19-2 t-butyl 4-hydroxy piperidine-1-carboxylate 
• 308386-38-1 tert-butyl 4-(4-bromophenoxy) piperidine-1-carboxylate 
• 5382-16-1 4-HYDROXYPIPERIDINE 
• 460-00-4 1-Bromo-4-fluorobenzene 

Downstream Products

• 1430471-86-5 4-(4-bromophenoxy)piperidine-1-carbaldehyde 
• 1240042-02-7 4-(4-bromophenoxy)-1-ethylpiperidine 
• 1373010-41-3 1-isopropyl-4-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenoxy)piperidine 
• 1430471-87-6 4-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenoxy)piperidine-1-carbaldehyde 
• 1373010-28-6 4-(4-bromophenoxy)-1-isopropylpiperidine 
• 1430472-39-1 1-(4-(4-bromophenoxy)piperidin-1-yl)-2-methylpropan-2-ol 
• 74129-98-9 4-(4-Bromo-phenoxy)-1-phenylsulfanyl-piperidine 

Relevant academic research and scientific papers

ENZYME INHIBITORS

The present invention provides compounds of formula (I) compositions comprising such compounds; the use of such compounds in therapy; and methods of treating patients with such compounds; wherein R1, R2, R3, R4, R5, R6, R7, R8, R9 and R10 are as defined h

Method of preparing Quinoline-5,8-dione derivatives for TGase 2 inhibitor

I Is -5,8- of the quinoline, dione derivative compound. of Formula I, or a stereoisomer or a pharmaceutically acceptable salt thereof, wherein the compound of Formula, TGase 2 has, inhibitory effects TGase 2, and thus the pharmaceutical composition may be useful for preventing or treating disorders or diseases mediated by TGase 2 or inhibiting. (by machine translation)

Quinoline-5,8-dione derivatives for TGase 2 inhibitor, and the pharmaceutical composition comprising the same

The present invention relates to a quinolin-5,8-dione derivative compound represented by chemical formula I, an optical isomer thereof or a pharmaceutically acceptable salt thereof. The compound represented by chemical formula I of the present invention has a TGase 2 inhibitory effect, and the pharmaceutical composition comprising the same can be usefully used for preventing or treating disorders or diseases mediated by TGase 2 or response to TGase 2 inhibition.COPYRIGHT KIPO 2020

The discovery of orally bioavailable tyrosine threonine kinase (TTK) inhibitors: 3-(4-(heterocyclyl)phenyl)-1H-indazole-5-carboxamides as anticancer agents

The acetamido and carboxamido substituted 3-(1H-indazol-3-yl)benzenesulfonamides are potent TTK inhibitors. However, they display modest ability to attenuate cancer cell growth; their physicochemical properties, and attendant pharmacokinetic parameters, a

ARYLOXYALKYLCARBAMATE-TYPE DERIVATIVES, PREPARATION METHOD THEREOF AND USE OF SAME IN THERAPEUTICS

The invention relates to a compound of formula (I): [image] Wherein m, n, X, Y, R1, R2, R3 and R4 are as defined herein. The invention also relates to the use of same in therapeutics.